Research field (2)：
Functional biochemistry
, Biochemistry
Research keywords (8)：
環境因子
, 分子認識
, 溶液化学
, 相互作用解析
, 構造解析
, 機能性核酸
, RNA
, DNA
Research theme for competitive and other funds (16)：
2022 - 2027 Quantitative prediction of nucleic acid structures and functions affected by spaciotemporal environmental factors in cells
2021 - 2024 Elucidation of the mechanism for dimensional response genome across species regulated by nucleic acid structures
2021 - 2024 Elucidation of the mechanism for dimensional response genome
2021 - 2024 Elucidation of the mechanism for dimensional response genome using intracellular environmental evaluation systems and development of dimensional response genome bank
2020 - 2023 Development and utilization of the model system of disease cell for quantitative analysis of nucleic acid structures in cells
2020 - 2022 Do ion channels control the formation of non-canonical nucleic acids and gene expression?
2019 - 2022 Rational control of gene expressions by chemically regulating topologies of nucleic acid structures
2018 - 2021 Analysis and regulation of non-canonical nucleic acids under intracellular conditions
2018 - 2020 How do potassium ions regulate the formation for non-canonical structures of nucleic acids and tumor progressions?
2017 - 2020 Effect of chemical environment changes in cell on DNA structures and functions
2018 - 2020 核酸の非二重構造を調節し、がんの発症を制御するのは、カリウムイオンなのか
2016 - 2019 Analysis of Dimensional Code in Central Dogma based on Polymorphic Nucleic Acid Structures
2014 - 2017 Control of the formation for DNA base pairs by DNA interactions under ultimate environments
2012 - 2015 Construction of database of non-canonical structures of nucleic acids and its application for constructing artificial systems controlling biological reactions
2012 - 2014 Development of new DNA nano-switches based on the stabilization of A-T base pairs relative to G-C base pairs
2012 - 2014 Quantitative analysis for the high ordered-RNA structures under ultimate environments
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Papers (80)：
Hisae Tateishi-Karimata, Keiko Kawauchi, Shuntaro Takahashi, Naoki Sugimoto. Development of a Pseudocellular System to Quantify Specific Interactions Determining the G-Quadruplex Function in Cells. Journal of the American Chemical Society. 2024. 146. 12. 8005-8015
Dipanwita Banerjee, Hisae Tateishi-Karimata, Maria Toplishek, Tatsuya Ohyama, Saptarshi Ghosh, Shuntaro Takahashi, Marko Trajkovski, Janez Plavec, Naoki Sugimoto. In-Cell Stability Prediction of RNA/DNA Hybrid Duplexes for Designing Oligonucleotides Aimed at Therapeutics. Journal of the American Chemical Society. 2023. 145. 43. 23503-23518
Saptarshi Ghosh, Shuntaro Takahashi, Dipanwita Banerjee, Tatsuya Ohyama, Tamaki Endoh, Hisae Tateishi-Karimata, Naoki Sugimoto. Nearest-neighbor parameters for the prediction of RNA duplex stability in diverse in vitro and cellular-like crowding conditions. Nucleic acids research. 2023. 51. 9. 4101-4111
Yong Zhang, Hisae Tateishi-Karimata, Tamaki Endoh, Qiongli Jin, Kexin Li, Xiaoru Fan, Yingjun Ma, Limin Gao, Haiyan Lu, Zhiye Wang, et al. High-temperature adaptation of an OsNRT2.3 allele is thermoregulated by small RNAs. Science advances. 2022. 8. 47. eadc9785
Saki Matsumoto, Hisae Tateishi-Karimata, Naoki Sugimoto. DNA methylation is regulated by both the stability and topology of G-quadruplex. Chemical communications (Cambridge, England). 2022. 58. 89. 12459-12462
橋本佳樹, 取井猛流, 藤田ひな, 川内敬子, 建石寿枝, 杉本直己, 三好大輔. A Novel G4 Ligand Screening System with G4-selective Fluorescent Probe. 日本化学会春季年会講演予稿集(Web). 2022. 102nd
杉本渉, 桑本慎, 建石寿枝, 岩根敦子, 岩根敦子, 岩根敦子, 高橋宏隆, 三好大輔, 川内敬子. The function of rDNA G-quadruplex aggregates formed by nucleolar stress. 日本薬学会年会要旨集(Web). 2021. 141年会. 29V05-am10S
月生雅也, 取井猛流, 建石寿枝, 西方敬人, 杉本直己, 三好大輔, 川内敬子. Analysis of liquid-liquid phase separation phenomenon by interaction between rDNA-derived DNA G4 and RGG peptide. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
取井猛流, 杉本渉, 建石寿枝, 鶴田充生, 月生雅也, 村嶋貴之, 西方敬人, 杉本直己, 三好大輔, 川内敬子. Molecular mechanism of the G-quadruplex formation for ribosomal DNA. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
大山達也, 建石寿枝, 田中成典, 杉本直己, 杉本直己. Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (69): Analysis of interactions between RNA G-quadruplexes and dipeptide repeats related to neurodegenerative diseases. 日本化学会春季年会講演予稿集(Web). 2021. 101st
