Rchr
J-GLOBAL ID：201801007856254340   Update date: Nov. 05, 2025

Kawazu Masahito

カワヅ マサヒト | Kawazu Masahito
Affiliation and department：
Chiba Cancer Center

About Chiba Cancer Center


Research field  (1)： Tumor biology
Research theme for competitive and other funds  (28)：
  • 2025 - 2028 Reassessment of HLA Expression in Trophoblast Cells: Elucidating Pathophysiology and Identifying Novel Therapeutic Targets in Trophoblastic Diseases
  • 2025 - 2028 高悪性度子宮内膜癌の不均一性の理解を介した治療抵抗性機構の解明
  • 2025 - 2028 Elucidation of the MYB-driven regulatory program that defines epithelial and myoepithelial differentiation in adenoid cystic carcinoma.
  • 2024 - 2028 患者由来細胞を用いた頭頸部腺様嚢胞癌における遺伝子変異の機能的意義の解明
  • 2024 - 2027 Diagnostics of methylation-based predictive biomarkers in ovarian and endometrial carcinomas by using both tumors and liquid biopsy
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Papers (98)：
  • Daisuke Yoshimoto, Hitoshi Iuchi, Ayumi Taguchi, Kenbun Sone, Kana Tamai, Ayako Mori, Shuhei Kitamura, Anh Quynh. Duong, Aya Ishizaka, Misako Kusakabe, et al. Downregulation of HLA Class I Expression Through HLA-A DNA Methylation Is Associated with Reduced CD8+ T Cell Infiltration in Cervical Cancer. Cancer Immunology Research. 2025
  • Megumi Mogi, Katsushige Kawase, Hiroyoshi Y. Tanaka, Suguru Miyata, Satoko Takemoto, Hideki Ikeda, Eri Katayama, Yuki Nakamura, Ryuta Kojima, Takao Morinaga, et al. Pan-cancer analysis of RNA expression signatures associated with cancer tissue architecture. British Journal of Cancer. 2025
  • Katsushige Kawase, Shusuke Kawashima, Tatsuya Nishi, Takashi Inozume, Takao Morinaga, Masahito Kawazu, Toyoyuki Hanazawa, Yosuke Togashi. PI3K/Akt Signaling Pathway Regulates CD155 Expression Involved in Resistance to Cancer Immunotherapy. Cancer Immunology Research. 2025. 13. 10. 1640-1654
  • Shuhei Kitamura, Ayumi Taguchi, Kana Tamai, Yoko Yamamoto, Anh Quynh Duong, Daisuke Yoshimoto, Ayako Mori, Aya Ishizaka, Saki Tsuchimochi, Kenbun Sone, et al. DNA Methylation in Ovarian and Endometrial Cancers: Predictive and Mechanistic Roles in PARP Inhibitor and ICI Response. Cancer Science. 2025. 116. 11. 2929-2939
  • Saki Tsuchimochi, Yoko Yamamoto, Ayumi Taguchi, Masahito Kawazu, Kenbun Sone, Masako Ikemura, Kana Tamai, Shuhei Kitamura, Daisuke Yoshimoto, Sayuri Fukaya, et al. BRCA1 Promoter Methylation in Ovarian Cancer: Clinical Relevance and a Novel Diagnostic Approach Using Fragment Analysis. Cancer science. 2025. 116. 7. 1996-2007
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MISC (12)：
  • Masahito Kawazu. PacBio Asia Pacific Webinar Series “High Resolution HLA Typing allows insight into Immune Evasion in Colon Cancer”. 2022
  • 河津正人. 細胞の生理的機能とゲノム異常・エピゲノム異常の関連. 実験医学 西川博嘉(編)よい炎症・悪い炎症から捉え直すがんと免疫. 2022. 42. 10. 1539-1544
  • 河津正人. ゲノムの構成. 病理と臨床 矢田部恭・宇於崎宏・北川昌伸 監修 がんゲノム医療時代の分子腫瘍学. 2022. 40. 2-6
  • Masahito Kawazu. PacBio Virtual User Meeting, “Full-length Transcriptome Analysis of Breast Cancer with Iso-Seq”. 2021
  • 河津正人. マイクロサテライト高度不安定性大腸がんにおける主要組織適合性複合体異常. 癌と化学療法. 2021. 48. 1185-1190
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Patents (12)：
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Books (9)：
  • 入門腫瘍内科学(改訂第4版)
    南江堂 2025 ISBN:9784524210756
  • 新臨床腫瘍学(改訂第7版)
    南江堂 2024 ISBN:9784524204267
  • もっとよくわかる!腫瘍免疫学 : 発がん~がんの進展~治療 : がん免疫応答の変遷がストーリーでわかる
    羊土社 2023 ISBN:9784758122122
  • もっとよくわかる!腫瘍免疫学 : 発がん~がんの進展~治療 : がん免疫応答の変遷がストーリーでわかる
    羊土社 2023 ISBN:9784758122122
  • Cancer: Principles & Practice of Oncology Primer of the Molecular Biology of Cancer, 2nd Edition
    2017 ISBN:9784895928823
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Lectures and oral presentations  (131)：
  • Analysis of clonal evolution in endometrioid endometrial cancer
    (The 84th Annual meeting of the Japanese Cancer Assosiation 2025)
  • Intrapatient diversity of subclonal phenotypes in endometrial carcinomas
    (The 84th Annual meeting of the Japanese Cancer Assosiation 2025)
  • Immune evasion through mitokndorial transfer in the tumor microenvironment
    (The 84th Annual meeting of the Japanese Cancer Assosiation 2025)
  • Functional characterization of an endogenous retroviral gene expressed in melanoma
    (The 84th Annual meeting of the Japanese Cancer Assosiation 2025)
  • Spatial Single-cell Analysis through Collaboration by Clinician, Pathologist, and Researcher Enhance Precision Medicine
    (The 84th Annual meeting of the Japanese Cancer Assosiation 2025)
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