Shiga Hisashi

シガヒサシ | Shiga Hisashi

Affiliation and department：

Research field (1)： Gastroenterology

Research keywords (2)：炎症性腸疾患 , 消化器内科学

Research theme for competitive and other funds (2)：

2012 - 2014 クローン病難治化と粘膜内リンパ球におけるエピジェネティクス制御異常
2010 - 2012 潰瘍性大腸炎感受性遺伝子NKX2.3が感受性を亢進させる分子メカニズムの解明

Papers (40)：

Yoichi Kakuta, Yosuke Kawai, Daisuke Okamoto, Tetsuya Takagawa, Kentaro Ikeya, Hirotake Sakuraba, Atsushi Nishida, Shoko Nakagawa, Miki Miura, Takahiko Toyonaga, et al. NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Journal of gastroenterology. 2018. 53. 9. 1065-1078
Ishioka M, Watanabe N, Sawaguchi M, Fukuda S, Shiga H, Matsuhashi T, Jin M, Iijima K. Phlegmonous Gastritis: A Report of Three Cases with Clinical and Imaging Features. Internal medicine (Tokyo, Japan). 2018. 57. 15. 2185-2188
Miyazawa T, Shiga H, Kinouchi Y, Takahashi S, Tominaga G, Takahashi H, Takagi S, Obana N, Kikuchi T, Omori S, et al. Long-term course of inflammatory bowel disease after the Great East Japan Earthquake. Journal of gastroenterology and hepatology. 2018. 33. 12. 1956-1960
Jun Kusaka, Hisashi Shiga, Masatake Kuroha, Tomoya Kimura, Yoichi Kakuta, Katsuya Endo, Yoshitaka Kinouchi, Tooru Shimosegawa. Residual Lesions on Capsule Endoscopy Is Associated with Postoperative Clinical Recurrence in Patients with Crohn’s Disease. Digestive Diseases and Sciences. 2018. 63. 3. 768-774
Motoyuki Onodera, Katsuya Endo, Takeo Naito, Rintaro Moroi, Masatake Kuroha, Yoshitake Kanazawa, Tomoya Kimura, Hisashi Shiga, Yoichi Kakuta, Kenichi Negoro, et al. Tacrolimus Dose Optimization Strategy for Refractory Ulcerative Colitis Based on the Cytochrome P450 3A5 Polymorphism Prediction Using Trough Concentration after 24 Hours. Digestion. 2018. 97. 1. 90-96

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MISC (23)：

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Books (2)：

消化器画像診断アトラス
中山出版 2017
炎症性腸疾患の外科治療
株式会社メジカルビュー社 2013

Lectures and oral presentations (21)：

小腸内視鏡近年の進歩と課題カプセル内視鏡を用いた術後クローン病症例の活動性評価
(Gastroenterological Endoscopy 2017)
クローン病の術後再燃および再手術に影響を与えた因子の検討
(日本消化器病学会雑誌 2017)
小腸疾患内視鏡診療のストラテジークローン病術後早期からのカプセル内視鏡検査の有用性
(Gastroenterological Endoscopy 2016)
Genotyping of NUDT15 R139c Could Be a Companion Diagnostic Test for Thiopurine-Induced Leucopenia and Hair Loss in Japanese Patients With IBD
(GASTROENTEROLOGY 2015)
DNA Methylation Profiles of CD4+Effector Memory T-Cells Show Distinct Differences Between Crohn's Disease and Ulcerative Colitis
(GASTROENTEROLOGY 2015)

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Professional career (1)：

医学博士 (東北大学)

Work history (7)：

2018/06 - 現在東北大学病院消化器内科助教
2016/10 - 2018/05 Akita University
2015/10 - 2016/09 Akita University
2012/08 - 2015/09 東北大学病院消化器内科特任助手
2010/04 - 2012/07 東北大学病院消化器内科

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