Art

J-GLOBAL ID：201802212726592188   Reference number：18A1198824

Meta-Analysis of Fecal Microbiota and Metabolites in Experimental Colitic Mice during the Inflammatory and Healing Phases

炎症および治癒期の実験的coliticマウスにおける糞便微生物叢および代謝産物のメタ分析【JST・京大機械翻訳】

Author (11)： Osaka Toshifumi (Department of Microbiology and Immunology, Tokyo Women’s Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan) ,  Osaka Toshifumi (Department of Life Science and Medical Bioscience, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan) ,  Moriyama Eri (Department of Life Science and Medical Bioscience, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan) ,  Arai Shunichi (Department of Life Science and Medical Bioscience, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan) ,  Date Yasuhiro (RIKEN Center for Sustainable Resource Science, 1-7-22 Suehirocho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan) ,  Date Yasuhiro (Graduate School of Medical Life Science, Yokohama City University, 1-7-29 Suehirocho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan) ,  Yagi Junji (Department of Microbiology and Immunology, Tokyo Women’s Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan) ,  Kikuchi Jun (RIKEN Center for Sustainable Resource Science, 1-7-22 Suehirocho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan) ,  Kikuchi Jun (Graduate School of Medical Life Science, Yokohama City University, 1-7-29 Suehirocho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan) ,  Kikuchi Jun (Graduate School of Bioagricultural Sciences, Nagoya University, 1 Furo-cho, Chikusa-ku, Nagoya, Aichi 464-0810, Japan) ,  Tsuneda Satoshi (Department of Life Science and Medical Bioscience, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan)
Material： Nutrients (Web)
Volume： 9  Issue： 12  Page： 1329  Publication year： 2017 
JST Material Number： U7255A  ISSN： 2072-6643  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The imbalance of gut microbiot...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A1198824&from=J-GLOBAL&jstjournalNo=U7255A") }}

Thesaurus term： Enterobacteriaceae ,  organic acid ,  Bacteroidaceae ,  *meta-analysis ,  colitis(large intestine) ,  enteric microbe ,  enteritis ,  rRNA ,  Lactobacillus ,  *metabolite ,  culture(biology) ,  *inflammation ,  characterization ,  *microflora
Semi thesaurus term： メタボローム , 【Automatic Indexing@JST】

Author keywords (8)： gut microbiota ,  dysbiosis ,  inflammatory bowel disease ,  metabolome ,  meta 16S rRNA analysis ,  ¹H-NMR analysis ,  experimental colitic mice ,  Lactobacillus

JST classification (1)： Basic medicine on digestive system  (GH01020E)

Reference (56)：

• Jostins, L.; Ripke, S.; Weersma, R.K.; Duerr, R.H.; McGovern, D.P.; Hui, K.Y.; Lee, J.C.; Schumm, L.P.; Sharma, Y.; Anderson, C.A.; et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature 2012, 491, 119-124.
• Contractor, N.V.; Bassiri, H.; Reya, T.; Park, A.Y.; Baumgart, D.C.; Wasik, M.A.; Emerson, S.G.; Carding, S.R. Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development in colitis-free gnotobiotic IL-2-deficient mice. J. Immunol. 1998, 160, 385-394.
• Dianda, L.; Hanby, A.M.; Wright, N.A.; Sebesteny, A.; Hayday, A.C.; Owen, M.J. T cell receptor-alpha beta-deficient mice fail to develop colitis in the absence of a microbial environment. Am. J. Pathol. 1997, 150, 91-97.
• Song, F.; Ito, K.; Denning, T.L.; Kuninger, D.; Papaconstantinou, J.; Gourley, W.; Klimpel, G.; Balish, E.; Hokanson, J.; Ernst, P.B. Expression of the neutrophil chemokine KC in the colon of mice with enterocolitis and by intestinal epithelial cell lines: Effects of flora and proinflammatory cytokines. J. Immunol. 1999, 162, 2275-2280.
• Frank, D.N.; St. Amand, A.L.; Feldman, R.A.; Boedeker, E.C.; Harpaz, N.; Pace, N.R. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc. Natl. Acad. Sci. USA 2007, 104, 13780-13785.

Terms in the title (8)： 炎症 ,  治癒 ,  実験 ,  マウス ,  糞便 ,  微生物叢 ,  代謝産物 ,  メタ分析