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J-GLOBAL ID：201802216586632414   Reference number：18A1214765

Adsorptive filtration systems for effective removal of blood amyloid β: a potential therapy for Alzheimer’s disease

血液中のアミロイドβの効果的除去のための吸着濾過システム: アルツハイマー病の潜在的治療法

Author (14)： KITAGUCHI Nobuya (Fujita Health Univ., Aichi, JPN) ,  KAWAGUCHI Kazunori (Fujita Health Univ., Aichi, JPN) ,  YAMAZAKI Kazunori (Fujita Health Univ., Aichi, JPN) ,  KAWACHI Hiroshi (Fujita Health Univ., Aichi, JPN) ,  KAWACHI Hiroshi (Ogaki Municipal Hospital, Aichi, JPN) ,  SAKATA Miwa (Fujita Health Univ., Aichi, JPN) ,  KANEKO Megumi (Fujita Health Univ., Aichi, JPN) ,  KANEKO Megumi (Iwata City Hospital, Shizuoka, JPN) ,  KATO Masao (Fujita Health Univ., Aichi, JPN) ,  SAKAI Kazuyoshi (Fujita Health Univ., Aichi, JPN) ,  OHASHI Norimi (Ogaki Municipal Hospital, Aichi, JPN) ,  HASEGAWA Midori (Fujita Health Univ., Aichi, JPN) ,  HIKI Yoshiyuki (Fujita Health Univ., Aichi, JPN) ,  YUZAWA Yukio (Fujita Health Univ., Aichi, JPN)
Material： Journal of Artificial Organs  (J Artif Organs)
Volume： 21  Issue： 2  Page： 220-229  Publication year： 2018 
JST Material Number： L3970A  ISSN： 1434-7229  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： adsorptive removal ,...

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JST classification (1)： Treatment for nervous system diseases in general  (GN05010N)

Reference (12)：

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• Mawuenyega KG, Sigurdson W, Ovod V, Munsell L, Kasten T, Morris JC, Yarasheski KE, Bateman RJ. Decreased clearance of CNS β-amyloid in Alzheimer’s disease. Science. 2010;330:1774.
• Sevigny J, Chiao P, Bussière T, Weinreb PH, Williams L, Maier M, Dunstan R, Salloway S, Chen T, Ling Y, O’Gorman J, Qian F, Arastu M, Li M, Chollate S, Brennan MS, Quintero-Monzon O, Scannevin RH, Arnold HM, Engber T, Rhodes K, Ferrero J, Hang Y, Mikulskis A, Grimm J, Hock C, Nitsch RM, Sandrock A. The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease. Nature. 2016;537:50-6.

Terms in the title (6)： 血液 ,  アミロイドβ ,  吸着 ,  濾過システム ,  アルツハイマー ,  治療法