Art

J-GLOBAL ID：201802226565166680   Reference number：18A1014086

Efficacy and Safety of Pitavastatin in Children and Adolescents with Familial Hypercholesterolemia in Japan and Europe

日本とヨーロッパにおける家族性高コレステロール血症の小児と青年でのピタバスタチンの有効性と安全性

Author (10)： Harada-Shiba Mariko (Department of Molecular Innovation in Lipidology, National Cerebral and Cardiovascular Center Research Institute) ,  Kastelein John J.P. (Department of Vascular Medicine, Academic Medical Center, University of Amsterdam) ,  Hovingh G. Kees (Department of Vascular Medicine, Academic Medical Center, University of Amsterdam) ,  Ray Kausik K. (Department of Primary Care and Public Health, School of Public Health, Imperial College London) ,  Ohtake Akira (Department of Pediatrics, Faculty of Medicine, Saitama Medical University) ,  Arisaka Osamu (Department of Pediatrics, Dokkyo Medical University School of Medicine) ,  Ohta Takao (Department of Child Health and Welfare (Pediatrics), Faculty of Medicine, University of the Ryukyu) ,  Okada Tomoo (Department of Pediatrics and Child Health, Nihon University School of Medicine) ,  Suganami Hideki (Clinical Data Science Department, Kowa Company, Ltd.) ,  Wiegman Albert (Department of Pediatrics, Academic Medical Center, University of Amsterdam)
Material： Journal of Atherosclerosis and Thrombosis (Web)  (J Atheroscler Thromb (Web))
Volume： 25  Issue： 5  Page： 422-429(J-STAGE)  Publication year： 2018 
JST Material Number： U0153A  ISSN： 1880-3873  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...

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Author keywords (5)： Familial hypercholesterolemia ,  Children ,  Pitavastatin ,  Low-density lipoprotein cholesterol ,  Ethnic difference

JST classification (1)： Treatment for metabolic diseases,nutritional diseases.  (GD05030F)

Substance index (1)： Pitavastatin

Reference (24)：

• 1) Harada-Shiba M, Arai H, Oikawa S, Ohta T, Okada T, Okamura T, Nohara A, Bujo H, Yokote K, Wakatsuki A, Ishibashi S and Yamashita S: Guidelines for the management of familial hypercholesterolemia. J Atheroscler Thromb, 2012; 19: 1043-1060
• 2) Nordestgaard BG, Chapman MJ, Humphries SE, Ginsberg HN, Masana L, Descamps OS, Wiklund O, Hegele RA, Raal FJ, Defesche JC, Wiegman A, Santos RD, Watts GF, Parhofer KG, Hovingh GK, Kovanen PT, Boileau C, Averna M, Boren J, Bruckert E, Catapano AL, Kuivenhoven JA, Pajukanta P, Ray K, Stalenhoef AF, Stroes E, Taskinen MR and Tybjaerg-Hansen A: Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society. Eur Heart J, 2013; 34: 3478-3490a
• 3) Mabuchi H, Nohara A, Noguchi T, Kobayashi J, Kawashiri MA, Tada H, Nakanishi C, Mori M, Yamagishi M, Inazu A and Koizumi J: Molecular genetic epidemiology of homozygous familial hypercholesterolemia in the Hokuriku district of Japan. Atherosclerosis, 2011; 214: 404-407
• 4) Zhou M and Zhao D: Familial Hypercholesterolemia in Asian Populations. J Atheroscler Thromb, 2016; 23: 539-549
• 5) Harada-Shiba M, Arai H, Okamura T, Yokote K, Oikawa S, Nohara A, Okada T, Ohta T, Bujo H, Watanabe M, Wakatsuki A and Yamashita S: Multicenter study to determine the diagnosis criteria of heterozygous familial hypercholesterolemia in Japan. J Atheroscler Thromb, 2012; 19: 1019-1026

Terms in the title (8)： 日本 ,  ヨーロッパ ,  家族性高コレステロール血症 ,  小児 ,  青年 ,  ピタバスタチン ,  有効性 ,  安全性