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J-GLOBAL ID：201802227362266124   Reference number：18A2070734

Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability

doublコルチン様キナーゼ1はDNA修復を損ない,染色体不安定性を誘導する【JST・京大機械翻訳】

Author (10)： Lu Yuxiong (Department of Medical Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8519, Japan) ,  Maruyama Junichi (Department of Medical Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8519, Japan) ,  Kuwata Keiko (Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Nagoya 464-8601, Japan) ,  Fukuda Hiroyuki (Agilent Technologies Research Alliance Laboratory, Graduate School of Science, Osaka University, Osaka 565-0871, Japan) ,  Fukuda Hiroyuki (Agilent Technologies Japan, Ltd., Hachioji-shi, Tokyo 192-8510, Japan) ,  Iwasa Hiroaki (Department of Medical Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8519, Japan) ,  Arimoto-Matsuzaki Kyoko (Department of Medical Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8519, Japan) ,  Sugimura Haruhiko (Department of Tumor Pathology, Hamamatsu University School of Medicine, Hamamatsu 431-3152, Japan) ,  Hata Yutaka (Department of Medical Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8519, Japan) ,  Hata Yutaka (Center for Brain Integration Research, Tokyo Medical and Dental University, Tokyo 113-8519, Japan)
Material： Biochemistry and Biophysics Reports
Volume： 16  Page： 130-137  Publication year： 2018 
JST Material Number： W3090A  ISSN： 2405-5808  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Doublecortin-like kinase 1 (DC...

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Thesaurus term： tumor ,  tumor cell ,  microtubule ,  *DNA Repair ,  colonic neoplasm ,  *instability ,  tumorigenesis ,  serine-threonine kinase ,  epithelium ,  Breast ,  chromatin ,  reconstitution ,  human ,  lung tumor ,  *kinase ,  membrane and film ,  histomembrane

Author keywords (3)： Chromatin instability ,  DCLK1 ,  DNA repair

JST classification (2)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Carcinogenic mechanisms and factors  (GE02020C)

Terms in the title (5)： コルチン ,  キナーゼ ,  DNA修復 ,  染色体不安定性 ,  誘導