Art

J-GLOBAL ID：201802233247242922   Reference number：18A1231795

Angubindin-1 opens the blood-brain barrier in vivo for delivery of antisense oligonucleotide to the central nervous system

アングビンジン-1はin vivoにおいて中枢神経系へのアンチセンスオリゴヌクレオチドの送達のために血液脳関門を開く

Author (19)： Zeniya Satoshi (Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan) ,  Zeniya Satoshi (Center for Brain Integration Research, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan) ,  Kuwahara Hiroya (Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan) ,  Kuwahara Hiroya (Center for Brain Integration Research, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan) ,  Daizo Kaiichi (Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan) ,  Daizo Kaiichi (Center for Brain Integration Research, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan) ,  Watari Akihiro (Graduate School of Pharmaceutical Sciences, Osaka University, Address: 1-6, Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Kondoh Masuo (Graduate School of Pharmaceutical Sciences, Osaka University, Address: 1-6, Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Yoshida-Tanaka Kie (Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan) ,  Yoshida-Tanaka Kie (Center for Brain Integration Research, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan) ,  Kaburagi Hidetoshi (Department of Orthopaedic and Spinal Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan) ,  Asada Ken (Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan) ,  Asada Ken (Center for Brain Integration Research, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan) ,  Nagata Tetsuya (Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan) ,  Nagata Tetsuya (Center for Brain Integration Research, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan) ,  Nagahama Masahiro (Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan) ,  Yagi Kiyohito (Graduate School of Pharmaceutical Sciences, Osaka University, Address: 1-6, Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Yokota Takanori (Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan) ,  Yokota Takanori (Center for Brain Integration Research, Tokyo Medical and Dental University (TMDU), Address: 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan)
Material： Journal of Controlled Release  (J Control Release)
Volume： 283  Page： 126-134  Publication year： Aug. 10, 2018 
JST Material Number： C0308D  ISSN： 0168-3659  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： mouse(animal) ,...
Semi thesaurus term： drug transport ,...

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Author keywords (6)： Antisense oligonucleotide ,  Angubindin-1 ,  Blood-brain barrier ,  Tricellular tight junction ,  Angulin-1 ,  Tricellulin

JST classification (1)： Basic biopharmacy  (GY01021U)

Terms in the title (4)： 中枢神経系 ,  アンチセンスオリゴヌクレオチド ,  送達 ,  血液脳関門