Art

J-GLOBAL ID：201802249601010726   Reference number：18A0053356

Angubindin-1, a novel paracellular absorption enhancer acting at the tricellular tight junction

3細胞タイトジャンクションに作用するアンギュビンディン-1という新規傍細胞吸収促進剤

Author (13)： Krug Susanne M. (Institute of Clinical Physiology, Department of Gastroenterology, Rheumatology and Infectious Diseases, Campus Benjamin Franklin, Charite - Universitaetsmedizin Berlin, 12203 Berlin, Germany) ,  Hayaishi Tomohiro (Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan) ,  Iguchi Daisuke (Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan) ,  Watari Akihiro (Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan) ,  Takahashi Azusa (Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan) ,  Fromm Michael (Institute of Clinical Physiology, Department of Gastroenterology, Rheumatology and Infectious Diseases, Campus Benjamin Franklin, Charite - Universitaetsmedizin Berlin, 12203 Berlin, Germany) ,  Nagahama Masahiro (Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan) ,  Takeda Hiroyuki (Proteo-Science Center, Ehime University, Ehime 790-8577, Japan) ,  Okada Yoshiaki (Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan) ,  Sawasaki Tatsuya (Proteo-Science Center, Ehime University, Ehime 790-8577, Japan) ,  Doi Takefumi (Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan) ,  Yagi Kiyohito (Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan) ,  Kondoh Masuo (Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan)
Material： Journal of Controlled Release  (J Control Release)
Volume： 260  Page： 1-11  Publication year： Aug. 28, 2017 
JST Material Number： C0308D  ISSN： 0168-3659  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *cell junction ,...
Semi thesaurus term： *アンギュビンディン1 ,...

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Author keywords (4)： Absorption enhancer ,  Tight junction ,  Paracellular passage ,  Mucosal absorption

JST classification (1)： Basic biopharmacy  (GY01021U)

Reference (40)：

• D.W. Powell, Barrier function of epithelia, Am. J. Phys. 241 (1981) G275-G288.
• E. Windsor, G.E. Cronheim, Gastro-intestinal absorption of heparin and synthetic heparinoids, Nature 190 (1961) 263-264.
• L.A. Staehelin, T.M. Mukherjee, A.W. Williams, Freeze-etch appearance of the tight junctions in the epithelium of small and large intestine of mice, Protoplasma 67 (1969) 165-184.
• D.S. Friend, N.B. Gilula, Variations in tight and gap junctions in mammalian tissues, J. Cell Biol. 53 (1972) 758-776.
• L.A. Staehelin, Further observations on the fine structure of freeze-cleaved tight junctions, J. Cell Sci. 13 (1973) 763-786.

Terms in the title (4)： 細胞 ,  タイトジャンクション ,  傍細胞 ,  吸収促進剤