Art

J-GLOBAL ID：201802257245203041   Reference number：18A0227132

The age-related changes of dietary phosphate responsiveness in plasma 1,25-dihydroxyvitamin D levels and renal Cyp27b1 and Cyp24a1 gene expression is associated with renal α-Klotho gene expression in mice

血漿1,25-ジヒドロキシビタミンD濃度および腎Cyp27b1およびCyp24a1遺伝子発現における食事性リン酸応答性の加齢変化は,マウスにおける腎α-Klotho遺伝子発現と関連する

Author (15)： Yoshikawa Ryouhei (Department of Clinical Nutrition and Food Management, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Yamamoto Hironori (Department of Clinical Nutrition and Food Management, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Yamamoto Hironori (Department of Health and Nutrition, Faculty of Human Life, Jin-ai University) ,  Yamamoto Hironori (Department of Nephrology, Faculty of Medical Sciences, University of Fukui) ,  Nakahashi Otoki (Department of Clinical Nutrition and Food Management, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Nakahashi Otoki (Division of Functional Food Chemistry, Institute for Health Science, Tokushima Bunri University) ,  Kagawa Tomohiro (Department of Clinical Nutrition and Food Management, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Tajiri Mari (Department of Clinical Nutrition and Food Management, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Nakao Mari (Department of Clinical Nutrition and Food Management, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Fukuda Shiori (Department of Clinical Nutrition and Food Management, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Arai Hidekazu (Laboratory of Clinical Nutrition and Management, Graduate School of Nutritional and Environmental Sciences, The University of Shizuoka) ,  Masuda Masashi (Department of Clinical Nutrition and Food Management, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Iwano Masayuki (Department of Nephrology, Faculty of Medical Sciences, University of Fukui) ,  Takeda Eiji (Department of Clinical Nutrition and Food Management, Institute of Biomedical Sciences, University of Tokushima Graduate School) ,  Taketani Yutaka (Department of Clinical Nutrition and Food Management, Institute of Biomedical Sciences, University of Tokushima Graduate School)
Material： Journal of Clinical Biochemistry and Nutrition  (JCBN)
Volume： 62  Issue： 1  Page： 68-74(J-STAGE)  Publication year： 2018 
JST Material Number： X0851A  ISSN： 0912-0009  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Mus musculus ,...
Semi thesaurus term： CYP24A1 ,...

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Author keywords (5)： α-Klotho ,  age-related change ,  vitamin D metabolism ,  inorganic phosphate ,  mice

JST classification (2)： Vitamin D  (EB07050H) ,  Animal metabolism and nutrition in general  (EJ02031R)

Reference (49)：

• 1 Dusso AS, Brown AJ, Slatopolsky E. Vitamin D. Am J Physiol Renal Physiol 2005; 289: F8-F28.
• 2 Miller WL. Genetic disorders of Vitamin D biosynthesis and degradation. J Steroid Biochem Mol Biol 2017; 165(Pt A): 101-108.
• 3 Christakos S, Dhawan P, Verstuyf A, Verlinden L, Carmeliet G. Vitamin D: Metabolism, molecular mechanism of action, and pleiotropic effects. Physiol Rev 2016; 96: 365-408.
• 4 Holick MF. Vitamin D deficiency. N Engl J Med 2007; 357: 266-281.
• 5 Takeda E, Yamamoto H, Nashiki K, Sato T, Arai H, Taketani Y. Inorganic phosphate homeostasis and the role of dietary phosphorus. J Cell Mol Med 2004; 8: 191-200.

Terms in the title (11)： 血漿 ,  腎 ,  CYP27B1 ,  CYP24A1 ,  遺伝子発現 ,  食事 ,  リン酸 ,  応答性 ,  加齢変化 ,  マウス ,  α-Klotho