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J-GLOBAL ID：201802260453946181   Reference number：18A0856919

Loss of Sfpq Causes Long-Gene Transcriptopathy in the Brain

SFPQの消失は脳における長い遺伝子のトランスクリプトームを引き起こす【JST・京大機械翻訳】

Author (15)： Takeuchi Akihide (Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan) ,  Iida Kei (Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan) ,  Iida Kei (Medical Research Support Center, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan) ,  Tsubota Toshiaki (Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan) ,  Hosokawa Motoyasu (Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan) ,  Denawa Masatsugu (Medical Research Support Center, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan) ,  Brown J.B. (Laboratory for Molecular Biosciences, Life Science Informatics Research Unit, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan) ,  Ninomiya Kensuke (Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan) ,  Ito Mikako (Division of Neurogenetics, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Kimura Hiroshi (Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama 226-8501, Japan) ,  Abe Takaya (Genetic Engineering Team, RIKEN Center for Life Science Technologies, Kobe 650-0047, Japan) ,  Kiyonari Hiroshi (Genetic Engineering Team, RIKEN Center for Life Science Technologies, Kobe 650-0047, Japan) ,  Kiyonari Hiroshi (Animal Resource Development Unit, R IKEN Center for Life Science Technologies, Kobe 650-0047, Japan) ,  Ohno Kinji (Division of Neurogenetics, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Hagiwara Masatoshi (Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan)
Material： Cell Reports
Volume： 23  Issue： 5  Page： 1326-1341  Publication year： 2018 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Genes specifically expressed i...

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Thesaurus term： regulatory gene ,  RNA binding protein ,  neuron ,  psychotic disorder ,  *gene ,  Down-Regulation ,  Phenotype ,  RNA Polymerase II ,  intron ,  targeting ,  nervous system disease ,  *Transcriptome ,  interaction ,  Neurodegenerative Diseases
Semi thesaurus term： 神経変性 , 【Automatic Indexing@JST】

Author keywords (10)： RNA-binding protein ,  transcriptional regulation ,  RNA polymerase II ,  cyclin-dependent kinase 9 ,  RBP/transcript-dependent elongation ,  long-gene transcriptotherapy ,  neuronal development ,  neurological and psychiatric diseases ,  long-gene diseases ,  long genopathies

JST classification (1)： Gene expression  (EC02040Q)

Terms in the title (3)： 脳 ,  遺伝子 ,  トランスクリプトーム