Art

J-GLOBAL ID：201802266748335901   Reference number：18A0116437

Genetic Variants of RAMP2 and CLR are Associated with Stroke

RAMP2とCLRの遺伝的変異体は脳卒中と関連している

Author (35)： Koyama Teruhide (Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine) ,  Kuriyama Nagato (Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine) ,  Ozaki Etsuko (Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine) ,  Matsui Daisuke (Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine) ,  Watanabe Isao (Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine) ,  Takeshita Wakiko (Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine) ,  Iwai Komei (Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine) ,  Watanabe Yoshiyuki (Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine) ,  Nakatochi Masahiro (Center for Advanced Medicine and Clinical Research, Nagoya University Hospital) ,  Shimanoe Chisato (Department of Preventive Medicine, Faculty of Medicine, Saga University) ,  Tanaka Keitaro (Department of Preventive Medicine, Faculty of Medicine, Saga University) ,  Oze Isao (Division of Molecular and Clinical Epidemiology, Aichi Cancer Center Research Institute) ,  Ito Hidemi (Division of Molecular and Clinical Epidemiology, Aichi Cancer Center Research Institute) ,  Uemura Hirokazu (Department of Preventive Medicine, Institute of Biomedical Sciences, Tokushima University Graduate School) ,  Katsuura-Kamano Sakurako (Department of Preventive Medicine, Institute of Biomedical Sciences, Tokushima University Graduate School) ,  Ibusuki Rie (Department of International Islands and Community Medicine, Kagoshima University Graduate School of Medical and Dental Sciences) ,  Shimoshikiryo Ippei (Department of International Islands and Community Medicine, Kagoshima University Graduate School of Medical and Dental Sciences) ,  Takashima Naoyuki (Department of Public Health, Shiga University of Medical Science) ,  Kadota Aya (Department of Public Health, Shiga University of Medical Science) ,  Kadota Aya (Center for Epidemiologic Research in Asia, Shiga University of Medical Science) ,  Kawai Sayo (Department of Preventive Medicine, Nagoya University Graduate School of Medicine) ,  Sasakabe Tae (Department of Preventive Medicine, Nagoya University Graduate School of Medicine) ,  Okada Rieko (Department of Preventive Medicine, Nagoya University Graduate School of Medicine) ,  Hishida Asahi (Department of Preventive Medicine, Nagoya University Graduate School of Medicine) ,  Naito Mariko (Department of Preventive Medicine, Nagoya University Graduate School of Medicine) ,  Kuriki Kiyonori (Laboratory of Public Health, School of Food and Nutritional Sciences, University of Shizuoka) ,  Endoh Kaori (Laboratory of Public Health, School of Food and Nutritional Sciences, University of Shizuoka) ,  Furusyo Norihiro (Department of Environmental Medicine and Infectious Disease, Kyushu University) ,  Ikezaki Hiroaki (Department of Environmental Medicine and Infectious Disease, Kyushu University) ,  Suzuki Sadao (Department of Public Health, Nagoya City University Graduate School of Medical Sciences) ,  Hosono Akihiro (Department of Public Health, Nagoya City University Graduate School of Medical Sciences) ,  Mikami Haruo (Cancer Prevention Center, Chiba Cancer Center Research Institute) ,  Nakamura Yohko (Cancer Prevention Center, Chiba Cancer Center Research Institute) ,  Kubo Michiaki (Laboratory for Genotyping Development, Center for Integrative Medical Sciences, RIKEN) ,  Wakai Kenji (Department of Preventive Medicine, Nagoya University Graduate School of Medicine)
Material： Journal of Atherosclerosis and Thrombosis (Web)  (J Atheroscler Thromb (Web))
Volume： 24  Issue： 12  Page： 1267-1281(J-STAGE)  Publication year： 2017 
JST Material Number： U0153A  ISSN： 1880-3873  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： *RAMP2

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Author keywords (4)： Adrenomedullin ,  Receptor activity-modifying protein 2 ,  Calcitonin-receptor-like receptor ,  Stroke

JST classification (1)： Nervous system diseases  (GN03000O)

Reference (50)：

• 1) Cleaver O and Melton DA: Endothelial signaling during development. Nat Med, 2003; 9: 661-668
• 2) Carmeliet P: Angiogenesis in health and disease. Nat Med, 2003; 9: 653-660
• 3) Miller AA, Budzyn K and Sobey CG: Vascular dysfunction in cerebrovascular disease: mechanisms and therapeutic intervention. Clin Sci (Lond), 2010; 119: 1-17
• 4) Higashi Y, Noma K, Yoshizumi M and Kihara Y: Endothelial function and oxidative stress in cardiovascular diseases. Circ J, 2009; 73: 411-418
• 5) Mochizuki N: Vascular integrity mediated by vascular endothelial cadherin and regulated by sphingosine 1-phosphate and angiopoietin-1. Circ J, 2009; 73: 2183-2191

Terms in the title (3)： RAMP2 ,  遺伝的変異体 ,  脳卒中