Art

J-GLOBAL ID：201802270312127115   Reference number：18A1077198

MicroRNA in Body Fluids-Development of the Novel Plat Form for Cancer Therapeutics and Diagnosis

がんの早期診断 体液MicroRNAを対象としたがんの早期診断方法の開発とその展望

Author (4)： TAKAHASHI RYOU (国立がん研究セ 研) ,  PRIETO-VILA Marta (国立がん研究セ 研) ,  KOHAMA ISSAKU (国立がん研究セ 研) ,  OCHIYA TAKAHIRO (国立がん研究セ 研)
Material： 癌と化学療法  (Japanese Journal of Cancer and Chemotherapy)
Volume： 45  Issue： 6  Page： 899-905  Publication year： Jun. 15, 2018 
JST Material Number： Z0938A  ISSN： 0385-0684  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： human(primates) ,...
Semi thesaurus term： Exosomes ,...

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JST classification (2)： Diagnosis of tumors(=neoplasms)  (GE03020J) ,  Molecular genetics in general  (EC02010J)

Reference (46)：

• Borchert GM, Lanier W and Davidson BL: RNA polymerase III transcribes human microRNAs. Nat Struct Mol Biol 13 (12) : 1097-1101, 2006.
• Zhang Y, Fan M, Zhang X, et al: Cellular microRNAs upregulate transcription via interaction with promoter TATA-box motifs. RNA 20 (12): 1878-1889, 2014.
• Valadi H, Ekström K, Bossios A, et al: Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 9 (6) : 654-659, 2007.
• Merchant ML, Rood IM, Deegens JKJ, et al: Isolation and characterization of urinary extracellular vesicles: implications for biomarker discovery. Nat Rev Nephrol 13 (12): 731-749, 2017.
• Villarroya-Beltri C, Gutiérrez-Vázquez C, Sánchez-Cabo F, et al: Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs. Nat Commun 4: 2980, 2013.

Terms in the title (6)： がん ,  早期診断 ,  体液 ,  microRNA ,  開発 ,  展望