Art

J-GLOBAL ID：201802273479944817   Reference number：18A0053145

Large-scale prospective pharmacogenomics study of oxaliplatin-induced neuropathy in colon cancer patients enrolled in the JFMC41-1001-C2 (JOIN Trial)

JFMC41-1001-C2(JOIN試験)登録結腸癌患者におけるオキサリプラチン誘導神経障害の大規模前向き薬理ゲノム学的研究

Author (19)： KANAI M. (Kyoto Univ., Kyoto) ,  KAWAGUCHI T. (Kyoto Univ., Kyoto) ,  KOTAKA M. (Sano Hospital, Kobe) ,  SHINOZAKI K. (Hiroshima Prefectural Hospital, Hiroshima) ,  TOUYAMA T. (Nakagami Hospital, Okinawa) ,  MANAKA D. (Kyoto-Katsura Hospital, Kyoto) ,  ISHIGURE K. (Konan Kosei Hospital Konan, Aichi) ,  HASEGAWA J. (Osaka Rosai Hospital, Osaka) ,  MUNEMOTO Y. (Fukui-ken Saiseikai Hospital, Fukui) ,  MATSUI T. (Aichi Cancer Center Aichi Hospital, Aichi) ,  TAKAGANE A. (Hakodate Goryoukaku Hospital, Hokkaido) ,  ISHIKAWA H. (Sasebo City General Hospital, Nagasaki) ,  MATSUMOTO S. (Kyoto Univ., Kyoto) ,  SAKAMOTO J. (Japanese Foundation for Multidisciplinary Treatment of Cancer, Tokyo) ,  SAJI S. (Japanese Foundation for Multidisciplinary Treatment of Cancer, Tokyo) ,  YOSHINO T. (National Cancer Center Hospital East, Chiba) ,  OHTSU A. (National Cancer Center, Chiba) ,  WATANABE T. (Univ. Tokyo, Tokyo, JPN) ,  MATSUDA F. (Kyoto Univ., Kyoto)
Material： Annals of Oncology  (Ann Oncol)
Volume： 27  Issue： 6  Page： 1143-1148  Publication year： Jun. 2016 
JST Material Number： W0107A  ISSN： 0923-7534  CODEN： ANONE2  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *neuropathy ,...
Semi thesaurus term： *Sensory peripheral neuropathy ,...

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JST classification (4)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Nervous system diseases  (GN03000O) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L)

Substance index (2)： Fluorouracil ,  Levofolinate calcium

Reference (27)：

• Andre T, Reyes-Vidal JM, Fartoux L et al. Gemcitabine and oxaliplatin in advanced biliary tract carcinoma: a phase II study. Br J Cancer 2008; 99: 862-867.
• Conroy T, Desseigne F, Ychou M et al. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N Engl J Med 2011; 364: 1817-1825.
• NCCN Clinical Practice Guideline: Colon Cancer. ver 3. 2015. http://www.nccn.org/professionals/physician_gls/pdf/colon.pdf 2014 (30 July 2015, date last accessed).
• Yamada Y, Higuchi K, Nishikawa K et al. Phase III study comparing oxaliplatin plus S-1 with cisplatin plus S-1 in chemotherapy-naive patients with advanced gastric cancer. Ann Oncol 2015; 26: 141-148.
• de Gramont A, Figer A, Seymour M et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 2000; 18: 2938-2947.

Terms in the title (10)： C2 ,  試験 ,  結腸癌 ,  患者 ,  オキサリプラチン ,  誘導 ,  神経障害 ,  大規模 ,  薬理ゲノム学 ,  研究