Art

J-GLOBAL ID：201502245566630135   Reference number：15A0468131

Phase III study comparing oxaliplatin plus S-1 with cisplatin plus S-1 in chemotherapy-naieve patients with advanced gastric cancer

進行胃癌の化学療法ナイーブ患者においてオキサリプラチン+S-1をシスプラチン+S-1と比較する第III相試験

Author (22)： YAMADA Y. (National Cancer Center Hospital, Tokyo) ,  HIGUCHI K. (Kitasato Univ. East Hospital, Sagamihara) ,  NISHIKAWA K. (Osaka General Medical Center, Osaka) ,  GOTOH M. (Osaka Medical Coll. Hospital, Takatsuki) ,  FUSE N. (National Cancer Center Hospital East, Kashiwa) ,  SUGIMOTO N. (Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka) ,  NISHINA T. (National Hospital Organization Shikoku Cancer Center, Matsuyama) ,  AMAGAI K. (Ibaraki Prefectural Central Hospital, Kasama) ,  CHIN K. (Cancer Inst. Hospital of JFCR, Tokyo) ,  NIWA Y. (Aichi Cancer Center Hospital, Nagoya) ,  TSUJI A. (Kochi Health Sci. Center, Kochi) ,  IMAMURA H. (Sakai City Hospital, Sakai) ,  TSUDA M. (Hyogo Cancer Center, Akashi) ,  YASUI H. (Shizuoka Cancer Center, Sunto-gun) ,  FUJII H. (Jichi Medical Univ., Shimotsuke) ,  YAMAGUCHI K. (Saitama Cancer Center, Kita-adachi-gun) ,  YASUI H. (National Hospital Organization Kyoto Medical Center, Kyoto) ,  HIRONAKA S. (Chiba Cancer Center, Chiba) ,  SHIMADA K. (Showa Univ. Northern Yokohama Hospital, Yokohama) ,  MIWA H. (Hyogo Coll. of Medicine, Nishinomiya) ,  HAMADA C. ,  HYODO I.
Material： Annals of Oncology  (Ann Oncol)
Volume： 26  Issue： 1  Page： 141-148  Publication year： Jan. 2015 
JST Material Number： W0107A  ISSN： 0923-7534  CODEN： ANONE2  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： RCT ,...

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JST classification (3)： Clinical application of antitumor(=antineoplastic)drugs  (GW16020L) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Tumors(=neoplasms)of digestive system  (GH04000D)

Substance index (1)： TS-1

Reference (16)：

• Waters JS, Norman A, Cunningham D et al. Long-term survival after epirubicin, cisplatin and fluorouracil for gastric cancer: results of a randomized trial. Br J Cancer 1999; 80: 269-272.
• Vanhoefer U, Rougier P, Wilke H et al. Final results of a randomized phase III trial of sequential high-dose methotrexate, fluorouracil, and doxorubicin versus etoposide, leucovorin, and fluorouracil versus infusional fluorouracil and cisplatin in advanced gastric cancer: a trial of the European Organization for Research and Treatment of Cancer Gastrointestinal Tract Cancer Cooperative Group. J Clin Oncol 2000; 18: 2648-2657.
• Van Cutsem E, Moiseyenko VM, Tjulandin S et al. Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 Study Group. J Clin Oncol 2006; 24: 4991-4997.
• Kang YK, Kang WK, Shin DB et al. Capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in patients with advanced gastric cancer: a randomised phase III noninferiority trial. Ann Oncol 2009; 20: 666-673.
• Al-Batran SE, Hartmann JT, Probst S et al. Phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil, leucovorin plus either oxaliplatin or cisplatin: a study of the Arbeitsgemeinschaft Internistische Onkologie. J Clin Oncol 2008; 26: 1435-1442.

Terms in the title (6)： 進行胃癌 ,  化学療法 ,  患者 ,  オキサリプラチン ,  シスプラチン ,  第III相試験