Art

J-GLOBAL ID：201802274173352481   Reference number：18A1595745

Whole-brain low-intensity pulsed ultrasound therapy markedly improves cognitive dysfunctions in mouse models of dementia - Crucial roles of endothelial nitric oxide synthase

全脳低強度パルス超音波療法は,認知症のマウスモデルにおける認知機能障害を著しく改善する-内皮一酸化窒素シンターゼの重要な役割【JST・京大機械翻訳】

Author (16)： Eguchi Kumiko (Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Shindo Tomohiko (Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Ito Kenta (Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Ogata Tsuyoshi (Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Kurosawa Ryo (Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Kagaya Yuta (Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Monma Yuto (Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Ichijo Sadamitsu (Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Kasukabe Sachie (Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Miyata Satoshi (Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Yoshikawa Takeo (Department of Pharmacology, Tohoku University School of Medicine Sendai, Japan) ,  Yanai Kazuhiko (Department of Pharmacology, Tohoku University School of Medicine Sendai, Japan) ,  Taki Hirofumi (Biomedical Engineering for Health and Welfare, Graduate School of Biomedical Engineering, Tohoku University, Sendai, Japan) ,  Kanai Hiroshi (Department of Electronic Engineering, Tohoku University Graduate School of Engineering, Sendai, Japan) ,  Osumi Noriko (Department of Developmental Neuroscience, Tohoku University, Sendai, Japan) ,  Shimokawa Hiroaki (Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan)
Material： Brain Stimulation
Volume： 11  Issue： 5  Page： 959-973  Publication year： 2018 
JST Material Number： W3152A  ISSN： 1935-861X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Therapeutic focused-ultrasound...

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Thesaurus term： *Endothelium ,  microglia ,  therapy ,  gene ,  *Dementia ,  knockout mouse ,  Eumetopias jubata ,  neurotrophic factor ,  amyloid beta-protein ,  pathological state ,  Western blotting ,  Alzheimer Disease ,  Up-Regulation ,  transgenic mouse ,  Nitric Oxide Synthase Type III ,  laboratory animal ,  Mus musculus ,  factor ,  bioactive factor ,  Amyloid ,  glycoprotein ,  animal protein ,  bioassay

Author keywords (3)： LIPUS ,  Dementia ,  eNOS

JST classification (1)： Basic neurology  (GN01020W)

Terms in the title (9)： 脳 ,  パルス ,  超音波療法 ,  認知症 ,  マウスモデル ,  認知機能障害 ,  内皮 ,  一酸化窒素シンターゼ ,  役割