Art

J-GLOBAL ID：201802278136258551   Reference number：18A1103466

Effects of a Dipeptidyl Peptidase 4 Inhibitor Sitagliptin on Glycemic Control and Lipoprotein Metabolism in Patients with Type 2 Diabetes Mellitus (GLORIA Trial)

2型糖尿病患者における血糖コントロールおよびリポ蛋白質代謝に対するジペプチジルペプチダーゼ4阻害剤シタグリプチンの効果(Gloria試験)

Author (20)： Masuda Daisaku (Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine) ,  Masuda Daisaku (Rinku General Medical Center) ,  Kobayashi Takuya (Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine) ,  Kobayashi Takuya (Rinku General Medical Center) ,  Sairyou Masami (Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine) ,  Hanada Hiroyuki (Division of Laboratory for Clinical Investigation, Department of Medical Technology, Osaka University Hospital) ,  Ohama Tohru (Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine) ,  Ohama Tohru (Department of Dental Anesthesiology, Osaka University Graduate School of Dentistry) ,  Koseki Masahiro (Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine) ,  Koseki Masahiro (Health Care Center, Osaka University) ,  Nishida Makoto (Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine) ,  Nishida Makoto (Health Care Center, Osaka University) ,  Maeda Norikazu (Department of Metabolism and Atherosclerosis, Osaka University Graduate School of Medicine) ,  Kihara Shinji (Department of Metabolism and Atherosclerosis, Osaka University Graduate School of Medicine) ,  Kihara Shinji (Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine) ,  Minami Tatsuya (Souseikai Sousei Hospital) ,  Yanagi Koji (Osaka Central Hospital) ,  Sakata Yasushi (Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine) ,  Yamashita Shizuya (Department of Community Medicine, Osaka University Graduate School of Medicine) ,  Yamashita Shizuya (Rinku General Medical Center)
Material： Journal of Atherosclerosis and Thrombosis (Web)  (J Atheroscler Thromb (Web))
Volume： 25  Issue： 6  Page： 512-520(J-STAGE)  Publication year： 2018 
JST Material Number： U0153A  ISSN： 1880-3873  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *lipoprotein metabolism ,...

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Author keywords (5)： Postprandial hypertriglyceridemia ,  DPP-4 ,  Sitagliptin ,  Lipoprotein Profile ,  Remnants

JST classification (2)： Treatment for metabolic diseases,nutritional diseases.  (GD05030F) ,  Clinical application of drugs acting on carbohydrate metabolism  (GW13030B)

Substance index (1)： Sitagliptin

Reference (35)：

• 1) Hata J, Ninomiya T, Hirakawa Y, Nagata M, Mukai N, Gotoh S, Fukuhara M, Ikeda F, Shikata K, Yoshida D, Yonemoto K, Kamouchi M, Kitazono T, Kiyohara Y: Secular trends in cardiovascular disease and its risk factors in Japanese: half-century data from the Hisayama Study (1961-2009). Circulation, 2013; 128: 1198-1205
• 2) Haffner SM, Lehto S, Rönnemaa T, Pyörälä K, Laakso M: Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med, 1998; 39(4): 229-234
• 3) Masuda D, Yamashita S: Postprandial hyperlipidemia and remnant lipoproteins. J Atheroscler Thromb, 2017; 24: 95-109
• 4) Schwartz GG, Abt M, Bao W, DeMicco D, Kallend D, Miller M, Mundl H, Olsson AG: Fasting triglycerides predict recurrent ischemic events in patients with acute coronary syndrome treated with statins. J Am Coll Cardiol, 2015; 65: 2267-2275
• 5) Watanabe N, Taniguchi T, Taketoh H, Kitagawa Y, Namura H, Yoneda N, Kurimoto Y, Yamada S, Ishikawa Y: Elevated remnant-like lipoprotein particles in impaired glucose tolerance and type 2 diabetic patients. Diabetes Care, 1999; 22: 152-156

Terms in the title (8)： 2型糖尿病 ,  患者 ,  血糖コントロール ,  リポ蛋白質代謝 ,  ジペプチジルペプチダーゼ4 ,  阻害剤 ,  シタグリプチン ,  試験