Art

J-GLOBAL ID：201802279298473995   Reference number：18A0986488

Rapid detection of mutation in isocitrate dehydrogenase 1 and 2 genes using mass spectrometry

質量分析を用いたイソクエン酸デヒドロゲナーゼ1および2における変異の迅速な検出

Author (11)： KANAMORI Masayuki (Tohoku Univ. Graduate School of Medicine, Miyagi, JPN) ,  MAEKAWA Masamitsu (Tohoku Univ. Hospital, Miyagi, JPN) ,  SHIBAHARA Ichiyo (Kitasato Univ. School of Medicine, Kanagawa, JPN) ,  SAITO Ryuta (Tohoku Univ. Graduate School of Medicine, Miyagi, JPN) ,  CHONAN Masashi (Tohoku Univ. Graduate School of Medicine, Miyagi, JPN) ,  SHIMADA Miki (Tottori Univ. Hospital, Tottori, JPN) ,  SONODA Yukihiko (Yamagata Univ. School of Medicine, Yamagata, JPN) ,  KUMABE Toshihiro (Kitasato Univ. School of Medicine, Kanagawa, JPN) ,  WATANABE Mika (Tohoku Univ. Hospital, Miyagi, JPN) ,  MANO Nariyasu (Tohoku Univ. Hospital, Miyagi, JPN) ,  TOMINAGA Teiji (Tohoku Univ. Graduate School of Medicine, Miyagi, JPN)
Material： Brain Tumor Pathology  (Brain Tumor Pathol)
Volume： 35  Issue： 2  Page： 90-96  Publication year： 2018 
JST Material Number： L2617A  ISSN： 1433-7398  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *isocitrate dehydrogenase ,...
Semi thesaurus term： LC/ESI-MS/MS ,...

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JST classification (1)： Neurologic diagnosis  (GN02000H)

Substance index (1)： 2-Hydroxyglutaric acid

Reference (26)：

• Louis DN, Ohgaki H, Wiestler OD et al (2016) WHO classification of tumours of the central nervous system. IARC Publications, Lyon
• Parsons DW, Jones S, Zhang X et al (2008) An integrated genomic analysis of human glioblastoma multiforme. Science 321:1807-1812
• Sonoda Y, Kumabe T, Nakamura T et al (2009) Analysis of IDH1 and IDH2 mutations in Japanese glioma patients. Cancer Sci 100:1996-1998
• Capper D, Sahm F, Hartmann C et al (2010) Application of mutant IDH1 antibody to differentiate diffuse glioma from nonneoplastic central nervous system lesions and therapy-induced changes. Am J Surg Pathol 34:1199-1204
• Horbinski C, Kelly L, Nikiforov YE et al (2010) Detection of IDH1 and IDH2 mutations by fluorescence melting curve analysis as a diagnostic tool for brain biopsies. J Mol Diagn 12:487-492

Terms in the title (3)： 質量分析 ,  イソクエン酸デヒドロゲナーゼ1 ,  変異