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J-GLOBAL ID：201802289128832595   Reference number：18A0158952

Direct In Vivo Reprogramming with Sendai Virus Vectors Improves Cardiac Function after Myocardial Infarction

センダイウイルスベクターを用いた直接in vivo再プログラミング心筋梗塞後の心臓機能を改善する【Powered by NICT】

Author (22)： Miyamoto Kazutaka (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Akiyama Mizuha (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Tamura Fumiya (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Isomi Mari (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Yamakawa Hiroyuki (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Sadahiro Taketaro (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Muraoka Naoto (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Kojima Hidenori (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Haginiwa Sho (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Kurotsu Shota (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Tani Hidenori (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Wang Li (Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599, USA) ,  Qian Li (Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599, USA) ,  Inoue Makoto (ID Pharma, Tsukuba, Ibaraki 300-2611, Japan) ,  Ide Yoshinori (Pharmacological Evaluation Institute of Japan, Center for Pharmacological Science, 3-25-22-424 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa 210-0821, Japan) ,  Kurokawa Junko (Department of Bio-informational Pharmacology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka-shi, Shizuoka 422-8526, Japan) ,  Yamamoto Tsunehisa (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Seki Tomohisa (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Aeba Ryo (Division of Cardiovascular Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Yamagishi Hiroyuki (Department of Pediatrics, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Fukuda Keiichi (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Ieda Masaki (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan)
Material： Cell Stem Cell
Volume： 22  Issue： 1  Page： 91-103.e5  Publication year： 2018 
JST Material Number： W3106A  ISSN： 1934-5909  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Direct cardiac reprogramming h...

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Thesaurus term： fibroblast ,  heartbeat ,  *Heart ,  regenerative medicine ,  fibrous disease ,  Cardiac Myocyte ,  gene introduction ,  *Respirovirus muris ,  *vector (genetics) ,  *Myocardial Infarction ,  human ,  gene expression ,  *infarct ,  Retroviridae ,  *reprogramming ,  *microorganism ,  *Parainfluenzavirus ,  *animal virus ,  *Paramyxovirus ,  molecular genetic phenomenon

Author keywords (7)： reprogramming ,  cardiomyocyte ,  Sendai virus ,  myocardial infarction ,  integration ,  fibroblast ,  regeneration

JST classification (1)： Gene manipulation  (EC02050B)

Terms in the title (4)： センダイウイルスベクター ,  再プログラミング ,  心筋梗塞 ,  心臓機能