Art

J-GLOBAL ID：201802289317780499   Reference number：18A2157589

Clinical Validation of Newly Developed Multiplex Kit Using Luminex xMAP Technology for Detecting Simultaneous RAS and BRAF Mutations in Colorectal Cancer: Results of the RASKET-B Study

結腸直腸癌における同時RASおよびBRAF変異を検出するためのLuminex XMAP技術を用いた新たに開発された多重キットの臨床的検証: RASKET-B研究の結果【JST・京大機械翻訳】

Author (16)： Taniguchi Hiroya (Department of Clinical Oncology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya-shi Aichi-ken, 464-8681, Japan) ,  Taniguchi Hiroya (Department of Gastrointestinal Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa-shi, Chiba-ken, 277-8577, Japan) ,  Okamoto Wataru (Biobank translational research support section, Translational research management division, Clinical Research Support Office, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa-shi, Chiba-ken, 277-8577, Japan) ,  Muro Kei (Department of Clinical Oncology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya-shi Aichi-ken, 464-8681, Japan) ,  Akagi Kiwamu (Division of Molecular Diagnosis and Cancer Prevention, Saitama Cancer Center, 818 Komuro, Ina-machi Kitaadachi-gun, Saitama-ken, 362-0806, Japan) ,  Hara Hiroki (Department of Gastroenterology, Saitama Cancer Center, 818 Komuro, Ina-machi Kitaadachi-gun, Saitama-ken, 362-0806, Japan) ,  Nishina Tomohiro (Department of Gastrointestinal Medical Oncology, National Hospital Organization Shikoku Cancer Center, 160 Kou, Minamiumemoto-machi, Matsuyama-shi, Ehime-ken, 791-0280, Japan) ,  Kajiwara Takeshi (Department of Gastrointestinal Medical Oncology, National Hospital Organization Shikoku Cancer Center, 160 Kou, Minamiumemoto-machi, Matsuyama-shi, Ehime-ken, 791-0280, Japan) ,  Denda Tadamichi (Division of Gastroenterology, Chiba Cancer Center Hospital, 666-2 Nitona-Cho, Chuo-ku, Chiba-ken, 260-8717, Japan) ,  Hironaka Shuichi (Department of Medical Oncology and Hematology, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu-shi, Oita-ken, 879-5593, Japan) ,  Kudo Toshihiro (Frontier Science for Cancer and Chemotherapy, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita-shi, Osaka-fu, 565-0871, Japan) ,  Satoh Taroh (Frontier Science for Cancer and Chemotherapy, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita-shi, Osaka-fu, 565-0871, Japan) ,  Yamanaka Takeharu (Department of Biostatistics, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama-shi, Kanagawa, 236-0004, Japan) ,  Abe Yukiko (Medical and Biological Laboratories Co. Ltd., KDX Nagoya Sakae Building 10F 4-5-3 Sakae, Naka-ku Nagoya-shi, Aichi-ken 460-0008, Japan) ,  Fukushima Yoshiyuki (Medical and Biological Laboratories Co. Ltd., KDX Nagoya Sakae Building 10F 4-5-3 Sakae, Naka-ku Nagoya-shi, Aichi-ken 460-0008, Japan) ,  Yoshino Takayuki (Department of Gastrointestinal Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa-shi, Chiba-ken, 277-8577, Japan)
Material： Neoplasia
Volume： 20  Issue： 12  Page： 1219-1226  Publication year： 2018 
JST Material Number： W3158A  ISSN： 1476-5586  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Detection of RAS and BRAF muta...

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Thesaurus term： Diagnosis ,  Mutation ,  therapeutic planning ,  statistics (science) ,  in vitro experiment ,  *multiplex ,  gene ,  simultaneous detection ,  direct sequencing method ,  end point ,  FFPE ,  genomic DNA ,  *Genetic Variation
Semi thesaurus term： *variation(biology) ,  転移性大腸癌 ,  *結腸直腸癌 , 【Automatic Indexing@JST】

JST classification (2)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Terms in the title (9)： 結腸直腸癌 ,  Ras ,  BRAF ,  変異 ,  開発 ,  多重 ,  臨床 ,  検証 ,  研究