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J-GLOBAL ID：201802294855890686   Reference number：18A1294866

Carbonate Apatite Nanoparticles Act as Potent Vaccine Adjuvant Delivery Vehicles by Enhancing Cytokine Production Induced by Encapsulated Cytosine-Phosphate-Guanine Oligodeoxynucleotides

炭酸アパタイトナノ粒子はカプセル化シトシン-ホスファート-グアニンオリゴデオキシヌクレオチドにより誘導されるサイトカイン産生増強により強力なワクチンアジュバントデリバリービークルとして作用する【JST・京大機械翻訳】

Author (16)： Takahashi Hideki (Vaccine Creation Project, BIKEN Innovative Vaccine Research Alliance Laboratories, Research Institute for Microbial Diseases, Osaka University) ,  Misato Kazuki (Vaccine Creation Project, BIKEN Innovative Vaccine Research Alliance Laboratories, Research Institute for Microbial Diseases, Osaka University) ,  Aoshi Taiki (Vaccine Dynamics Project, BIKEN Innovative Vaccine Research Alliance Laboratories, Research Institute for Microbial Diseases, Osaka University) ,  Aoshi Taiki (Vaccine Dynamics Project, BIKEN Center for Innovative Vaccine Research and Development, The Research Foundation for Microbial Diseases of Osaka University) ,  Yamamoto Yasuyuki (Vaccine Creation Project, BIKEN Center for Innovative Vaccine Research and Development, The Research Foundation for Microbial Diseases of Osaka University) ,  Kubota Yui (Division of Health Sciences, Department of Molecular Pathology, Graduate School of Medicine, Osaka University) ,  Wu Xin (Division of Health Sciences, Department of Molecular Pathology, Graduate School of Medicine, Osaka University) ,  Kuroda Etsushi (Laboratory of Adjuvant Innovation, Center for Vaccine and Adjuvant Research, National Institutes of Biomedical Innovation, Health and Nutrition) ,  Kuroda Etsushi (Laboratory of Vaccine Science, WPI Immunology Frontier Research Center, Osaka University) ,  Ishii Ken J. (Laboratory of Adjuvant Innovation, Center for Vaccine and Adjuvant Research, National Institutes of Biomedical Innovation, Health and Nutrition) ,  Ishii Ken J. (Laboratory of Vaccine Science, WPI Immunology Frontier Research Center, Osaka University) ,  Yamamoto Hirofumi (Division of Health Sciences, Department of Molecular Pathology, Graduate School of Medicine, Osaka University) ,  Yoshioka Yasuo (Vaccine Creation Project, BIKEN Innovative Vaccine Research Alliance Laboratories, Research Institute for Microbial Diseases, Osaka University) ,  Yoshioka Yasuo (Vaccine Creation Project, BIKEN Center for Innovative Vaccine Research and Development, The Research Foundation for Microbial Diseases of Osaka University) ,  Yoshioka Yasuo (Laboratory of Nano-Design for Innovative Drug Development, Graduate School of Pharmaceutical Sciences, Osaka University) ,  Yoshioka Yasuo (Global Center for Medical Engineering and Informatics, Osaka University)
Material： Frontiers in Immunology (Web)
Volume： 9  Page： 783  Publication year： 2018 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Vaccine adjuvants that can ind...

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Thesaurus term： *vaccine ,  *adjuvant ,  antibody ,  antigen ,  interferon gamma ,  *nano particle ,  in vitro experiment ,  Th1 cell ,  influenza virus ,  human ,  dendritic cell ,  Interleukin-12 ,  CpG ,  *cytokine production ,  immune response ,  microorganism
Semi thesaurus term： immunological reaction , 【Automatic Indexing@JST】

Author keywords (6)： adjuvant ,  cytosine-phosphate-guanine oligodeoxynucleotide ,  influenza virus ,  interferon-α ,  nanoparticle ,  vaccine

JST classification (2)： Basic research of immunotherapeutic agents and blood preparations  (GW22010D) ,  Immunological reaction in general  (ED03010T)

Terms in the title (10)： 炭酸アパタイト ,  ナノ粒子 ,  カプセル化 ,  シトシン ,  ホスファート ,  グアニン ,  オリゴデオキシヌクレオチド ,  誘導 ,  サイトカイン産生 ,  増強