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J-GLOBAL ID：201902208058069573   Reference number：19S0408103

I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3ß signaling pathway

Author (29)： Ohta, Etsuro (R and D Center for Cell Design, Institute for Regenerative Medicine and Cell Design, Kitasato University School of Allied Health Sciences) ,  Ohta, Etsuro (Division of Clinical Immunology, Graduate School of Medical Sciences, Kitasato University) ,  Ohta, Etsuro (Department of Physiology, Keio University School of Medicine) ,  Obata, Fumiya (R and D Center for Cell Design, Institute for Regenerative Medicine and Cell Design, Kitasato University School of Allied Health Sciences) ,  Obata, Fumiya (Division of Clinical Immunology, Graduate School of Medical Sciences, Kitasato University) ,  Nihira, Tomoko (Department of Neuro-Regenerative Medicine, Graduate School of Medical Sciences, Kitasato University) ,  Nihira, Tomoko (Department of Physiology, Keio University School of Medicine) ,  Hayakawa, Hideki (Department of Neuro-Regenerative Medicine, Graduate School of Medical Sciences, Kitasato University) ,  Mizuno, Yoshikuni (Department of Neuro-Regenerative Medicine, Graduate School of Medical Sciences, Kitasato University) ,  Uchino, Akiko (Department of Neurology, Graduate School of Medical Sciences, Kitasato University) ,  Uchino, Akiko (Department of the Brain Bank for Aging Research, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology) ,  Nishiyama, Kazutoshi (Department of Neurology, Graduate School of Medical Sciences, Kitasato University) ,  Nishiyama, Kazutoshi (Department of Neurology, Kitasato University School of Medicine) ,  Imaizumi, Yoichi (Department of Physiology, Keio University School of Medicine) ,  Okada, Yohei (Department of Physiology, Keio University School of Medicine) ,  Okada, Yohei (Department of Neurology, Aichi Medical University School of Medicine) ,  Akamatsu, Wado (Department of Physiology, Keio University School of Medicine) ,  Akamatsu, Wado (Center for Genomic and Regenerative Medicine, Juntendo University School of Medicine) ,  Okano, Hideyuki (Department of Physiology, Keio University School of Medicine) ,  Ohyama, Manabu (Department of Dermatology, Keio University School of Medicine) ,  Murayama, Shigeo (Department of the Brain Bank for Aging Research, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology) ,  Murayama, Shigeo (Department of Neurology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology) ,  Murayama, Shigeo (Department of Bioresource Center (the Brain Bank for Aging Research), Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology) ,  Takahashi, Kayoko (Department of Medical Laboratory, Kitasato University Hospital) ,  Nagai, Makiko (Department of Neurology, Kitasato University School of Medicine) ,  Ryo, Masafuchi (Department of Neurology, Kitasato University School of Medicine) ,  Ogino, Mieko (Department of Neurology, Kitasato University School of Medicine) ,  Takashima, Akihiko (Department of Neurobiology, National Center for Geriatrics and Gerontology) ,  Mochizuki, Hideki (Department of Neurology, Osaka University Graduate School of Medicine)
Material： Human Molecular Genetics
Volume： 24  Issue： 17  Page： 4879-4900  Publication year： 2015 
JST Material Number： SCOPUS  ISSN： 0964-6906  CODEN： HMGEE 
Country of issue： United Kingdom (GBR)  Language： English (EN)

Terms in the title (2)： LRRK2 ,  Akt