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J-GLOBAL ID：201902212369865764   Reference number：19A0647851

Neuroimaging-pathological correlations of [ 18 F]THK5351 PET in progressive supranuclear palsy

進行性上位麻痺における[18F]THK5351 PETの神経画像-病理学的相関【JST・京大機械翻訳】

Author (25)： Ishiki Aiko (Department of Geriatrics and Gerontology, Division of Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Harada Ryuichi (Department of Geriatrics and Gerontology, Division of Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Harada Ryuichi (Department of Pharmacology, Tohoku University School of Medicine, Sendai, Japan) ,  Harada Ryuichi (Department of Pharmacology, Tohoku University School of Medicine 2-1, Sendai, Japan) ,  Kai Hideaki (Department of Neurological Science, Tohoku University School of Medicine, Sendai, Japan) ,  Sato Naomi (Department of Pathology, Tohoku University School of Medicine, Sendai, Japan) ,  Totsune Tomoko (Department of Nuclear Medicine and Radiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Tomita Naoki (Department of Geriatrics and Gerontology, Division of Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Watanuki Shoichi (Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan) ,  Hiraoka Kotaro (Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan) ,  Ishikawa Yoichi (Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan) ,  Funaki Yoshihito (Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan) ,  Iwata Ren (Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan) ,  Furumoto Shozo (Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan) ,  Tashiro Manabu (Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan) ,  Sasano Hironobu (Department of Pathology, Tohoku University School of Medicine, Sendai, Japan) ,  Kitamoto Tetsuyuki (Department of Neurological Science, Tohoku University School of Medicine, Sendai, Japan) ,  Kudo Yukitsuka (Department of Geriatrics and Gerontology, Division of Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Yanai Kazuhiko (Department of Pharmacology, Tohoku University School of Medicine, Sendai, Japan) ,  Yanai Kazuhiko (Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan) ,  Furukawa Katsutoshi (Division of Community Medicine, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan) ,  Okamura Nobuyuki (Department of Pharmacology, Tohoku University School of Medicine, Sendai, Japan) ,  Okamura Nobuyuki (Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan) ,  Okamura Nobuyuki (Division of Pharmacology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan) ,  Arai Hiroyuki (Department of Geriatrics and Gerontology, Division of Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan)
Material： Acta Neuropathologica Communications (Web)
Volume： 6  Issue： 1  Page： 53  Publication year： 2018 
JST Material Number： U7296A  ISSN： 2051-5960  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Recent positron emission tomog...

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Thesaurus term： *paralytic disease ,  *image ,  *pathological state ,  death ,  globus pallidus ,  temporal lobe ,  PET(tomography) ,  in vitro experiment ,  standardization ,  cortex(animal tissue) ,  aphasia ,  astrocyte
Semi thesaurus term： 阻害剤 ,  *神経 ,  進行性核上麻痺 , 【Automatic Indexing@JST】

Author keywords (6)： PSP ,  Monoamine oxidase ,  Reactive astrocyte ,  Tau ,  PET ,  [18F]THK5351

JST classification (2)： Neurologic diagnosis  (GN02000H) ,  Radiodiagnosis  (GC04020K)

Reference (46)：

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• Front Aging Neurosci; [18F]-THK5351 PET correlates with topology and symptom severity in progressive supranuclear palsy; M Brendel, S Schonecker, G Hoglinger, S Lindner, J Havla, J Blautzik; 9; 2017; 440; 10.3389/fnagi.2017.00440; citation_id=CR2
• J Nucl Med; Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG; SF Carter, M Scholl, O Almkvist, A Wall, H Engler, B Langstrom; 53; 2012; 37-46; 10.2967/jnumed.110.087031; citation_id=CR3
• J Alzheimers Dis; Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807; DT Chien, S Bahri, AK Szardenings, JC Walsh, F Mu, MY Su; 34; 2013; 457-468; 10.3233/JAD-122059; citation_id=CR4
• Declercq L, Celen S, Lecina J, Ahamed M, Tousseyn T, Moechars D et al (2016) Comparison of new tau PET-tracer candidates with [18F]T808 and [18F]T807. Mol Imaging 15:1-15.

Terms in the title (5)： 麻痺 ,  PET ,  神経画像 ,  病理学 ,  相関