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J-GLOBAL ID：201902221585155424   Reference number：19A0217142

Tissue Distribution of Menaquinone-7 and the Effect of α-Tocopherol Intake on Menaquinone-7 Concentration in Rats

メナキノン-7の組織分布とラットにおけるメナキノン-7濃度に及ぼすα-トコフェロール摂取の影響

Author (7)： IKEDA Saiko (Department of Nutritional Sciences, Nagoya University of Arts and Sciences) ,  HANZAWA Fumiaki (Department of Nutritional Sciences, Nagoya University of Arts and Sciences) ,  TAKAHASHI Saki (Department of Nutritional Sciences, Nagoya University of Arts and Sciences) ,  SUZUKI Norie (Department of Nutritional Sciences, Nagoya University of Arts and Sciences) ,  SANO Kana (Department of Nutritional Sciences, Nagoya University of Arts and Sciences) ,  ODA Hiroaki (Graduate School of Bioagricultural Sciences, Nagoya University) ,  UCHIDA Tomono (Department of Home Economics, Aichi Gakusen University)
Material： Journal of Nutritional Science and Vitaminology (Web)
Volume： 64  Issue： 6  Page： 391-398(J-STAGE)  Publication year： 2018 
JST Material Number： U1313A  ISSN： 1881-7742  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： biodistribution ,...

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Author keywords (5)： menaquinone-4 ,  menaquinone-7 distribution ,  phylloquinone ,  vitamin E ,  vitamin K metabolism

JST classification (2)： Other vitamins  (EB07070D) ,  Animal metabolism and nutrition in general  (EJ02031R)

Substance index (4)： alpha-Tocopherol ,  Menatetrenone ,  Menaquinone 7 ,  Menadione

Reference (25)：

• 1) Kamao M, Suhara Y, Tsugawa N, Uwano M, Yamaguchi N, Uenishi K, Ishida H, Sasaki S, Okano T. 2007. Vitamin K content of foods and dietary vitamin K intake in Japanese young women. J Nutr Sci Vitaminol 53: 464-470.
• 2) Thijssen HH, Drittij-Reijnders MJ, Fischer MA. 1996. Phylloquinone and menaquinone-4 distribution in rats: synthesis rather than uptake determines menaquinone-4 organ concentrations. J Nutr 126: 537-543.
• 3) Yamamoto R, Komai M, Kojima K, Furukawa Y, Kimura S. 1997. Menaquinone-4 accumulation in various tissues after an oral administration of phylloquinone in Wistar rats. J Nutr Sci Vitaminol 43: 133-143.
• 4) Okano T, Shimomura Y, Yamane M, Suhara Y, Kamao M, Sugiura M, Nakagawa K. 2008. Conversion of phylloquinone (vitamin K1) into menaquinone-4 (vitamin K2) in mice: two possible routes for menaquinone-4 accumulation in cerebra of mice. J Biol Chem 283: 11270-11279.
• 5) Nakagawa K, Hirota Y, Sawada N, Yuge N, Watanabe M, Uchino Y, Okuda N, Shimomura Y, Suhara Y, Okano T. 2010. Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme. Nature 468: 117-121.

Terms in the title (4)： メナキノン-7 ,  組織分布 ,  ラット ,  α-トコフェロール