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J-GLOBAL ID：201902231727591735   Reference number：19A1349041

Neutrophil Depletion Exacerbates Pregnancy Complications, Including Placental Damage, Induced by Silica Nanoparticles in Mice

好中球枯渇はマウスにおけるシリカナノ粒子により誘導される胎盤損傷を含む妊娠合併症を悪化させる【JST・京大機械翻訳】

Author (18)： Higashisaka Kazuma (Laboratory of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan) ,  Higashisaka Kazuma (Department of Legal Medicine, Osaka University Graduate School of Medicine, Suita, Japan) ,  Nakashima Akitoshi (Department of Obstetrics and Gynecology, University of Toyama, Toyama, Japan) ,  Iwahara Yuki (Laboratory of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan) ,  Aoki Aiko (Department of Obstetrics and Gynecology, University of Toyama, Toyama, Japan) ,  Nakayama Masahiro (Department of Developmental Medicine, Research Institute, Osaka Women’s and Children’s Hospital, Izumi, Japan) ,  Yanagihara Itaru (Department of Developmental Medicine, Research Institute, Osaka Women’s and Children’s Hospital, Izumi, Japan) ,  Lin Ying (Laboratory of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan) ,  Nagano Kazuya (Laboratory of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan) ,  Tsunoda Shin-ichi (The Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Kobe, Japan) ,  Tsunoda Shin-ichi (Laboratory of Biopharmaceutical Research, National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki, Japan) ,  Tsunoda Shin-ichi (The Center for Advanced Medical Engineering and Informatics, Osaka University, Suita, Japan) ,  Saito Shigeru (Department of Obstetrics and Gynecology, University of Toyama, Toyama, Japan) ,  Yoshioka Yasuo (Laboratory of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan) ,  Yoshioka Yasuo (Vaccine Creation Project, BIKEN Innovative Vaccine Research Alliance Laboratories, Research Institute for Microbial Diseases, Osaka University, Suita, Japan) ,  Yoshioka Yasuo (BIKEN Center for Innovative Vaccine Research and Development, The Research Foundation for Microbial Diseases of Osaka University, Suita, Japan) ,  Tsutsumi Yasuo (Laboratory of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan) ,  Tsutsumi Yasuo (The Center for Advanced Medical Engineering and Informatics, Osaka University, Suita, Japan)
Material： Frontiers in Immunology (Web)
Volume： 9  Page： 1850  Publication year： 2018 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Recent advances in nanotechnol...

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Thesaurus term： vascular disease ,  Endothelium ,  *Placenta ,  Body Weight ,  pretreatment ,  *silicon dioxide ,  *Neutrophils ,  *Pregnancy ,  Fetus ,  *pregnancy complication ,  cytotoxicity ,  Apoptosis ,  antibody ,  *nano particle ,  isoform

Author keywords (5)： apoptosis ,  nanotoxicology ,  placenta ,  placental vessels ,  pregnancy complications

JST classification (2)： Immunological reaction in general  (ED03010T) ,  Biophylaxis and immune systems in general  (ED01010F)

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Terms in the title (9)： 好中球 ,  枯渇 ,  マウス ,  シリカナノ粒子 ,  誘導 ,  胎盤 ,  損傷 ,  妊娠合併症 ,  悪化