Art

J-GLOBAL ID：201902258066797194   Reference number：19A1100262

Clinical significance of ASXL2 and ZBTB7A mutations and C-terminally truncated RUNX1-RUNX1T1 expression in AML patients with t(8;21) enrolled in the JALSG AML201 study

JALSG AML201研究で登録されたT(8;21)を有するAML患者におけるASXL2およびZBTB7A変異およびC末端切断RUNX1-RUNX1T1発現の臨床的意義【JST・京大機械翻訳】

Author (26)： Kawashima Naomi (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Akashi Akimi (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Nagata Yasunobu (Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Nagata Yasunobu (Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA) ,  Kihara Rika (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Ishikawa Yuichi (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Asou Norio (Department of Hematology, International Medical Center, Saitama Medical University, Hidaka, Japan) ,  Ohtake Shigeki (Kanazawa University, Kanazawa, Japan) ,  Miyawaki Shuichi (Division of Hematology, Tokyo Metropolitan Ohtsuka Hospital, Tokyo, Japan) ,  Sakura Toru (Leukemia Research Center, Saiseikai Maebashi Hospital, Maebashi, Japan) ,  Ozawa Yukiyasu (Department of Hematology, Japanese Red Cross Nagoya First Hospital, Nagoya, Japan) ,  Usui Noriko (Division of Clinical Oncology and Hematology, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan) ,  Kanamori Heiwa (Department of Hematology, Kanagawa Cancer Center, Yokohama, Japan) ,  Ito Yoshikazu (Department of Hematology, Tokyo Medical University, Tokyo, Japan) ,  Imai Kiyotoshi (Department of Hematology, Sapporo Hokuyu Hospital, Sapporo, Japan) ,  Suehiro Youko (Department of Hematology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan) ,  Kitamura Kunio (Division of Hematology, Ichinomiya Municipal Hospital, Ichinomiya, Japan) ,  Sakaida Emiko (Department of Hematology, Chiba University Hospital, Chiba, Japan) ,  Takeshita Akihiro (Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan) ,  Suzushima Hitoshi (Department of Hematology, Kumamoto Shinto General Hospital, Kumamoto, Japan) ,  Naoe Tomoki (National Hospital Organization Nagoya Medical Center, Nagoya, Japan) ,  Matsumura Itaru (Department of Hematology and Rheumatology, Faculty of Medicine, Kindai University, Osaka, Japan) ,  Miyazaki Yasushi (Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan) ,  Ogawa Seishi (Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Kiyoi Hitoshi (Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  for the Japan Adult Leukemia Study Group (JALSG)
Material： Annals of Hematology
Volume： 98  Issue： 1  Page： 83-91  Publication year： 2019 
JST Material Number： W4037A  ISSN： 0939-5555  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： We analyzed the clinical signi...

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Thesaurus term： Heredity ,  Bone Marrow ,  Diagnosis ,  Mutation ,  acute myeloid leukemia ,  wild type ,  complex (substance) ,  Real Time Polymerase Chain Reaction ,  gene ,  transcript ,  Japanese ,  *Runx1 ,  *Genetic Variation
Semi thesaurus term： genetic variation ,  *variation(biology) ,  *JALSG , 【Automatic Indexing@JST】

Author keywords (5)： Acute myeloid leukemia ,  Core-binding factor ,  ASXL1/2 ,  ZBTB7A ,  RUNX1-RUX1T1 transcript

JST classification (1)： Blood cell tumors(=neoplasms)  (GK04000M)

Terms in the title (10)： JALSG ,  研究 ,  AML ,  患者 ,  変異 ,  C末端 ,  RUNX1 ,  RUNX1T1 ,  発現 ,  臨床的意義