Art

J-GLOBAL ID：201902284390018615   Reference number：19A0766071

Identification of Metabolites Associated with Onset of CAD in Diabetic Patients Using CE-MS Analysis: A Pilot Study

CE-MS分析を用いた糖尿病患者におけるCADの開始に関連する代謝産物の同定:パイロット研究

Author (11)： Omori Kazuo (Department of Metabolic Medicine, Osaka University Graduate School of Medicine) ,  Katakami Naoto (Department of Metabolic Medicine, Osaka University Graduate School of Medicine) ,  Katakami Naoto (Department of Metabolism and Atherosclerosis, Osaka University Graduate School of Medicine) ,  Yamamoto Yuichi (Department of Metabolic Medicine, Osaka University Graduate School of Medicine) ,  Ninomiya Hiroyo (Department of Metabolic Medicine, Osaka University Graduate School of Medicine) ,  Takahara Mitsuyoshi (Department of Metabolic Medicine, Osaka University Graduate School of Medicine) ,  Takahara Mitsuyoshi (Department of Diabetes Care Medicine, Graduate, School of Medicine, Osaka University) ,  Matsuoka Taka-aki (Department of Metabolic Medicine, Osaka University Graduate School of Medicine) ,  Bamba Takeshi (Division of Metabolomics, Medical Institute of Bioregulation, Kyushu University) ,  Fukusaki Eiichiro (Laboratory of Bioresource Engineering, Department of Biotechnology, Graduate School of Engineering, Osaka University) ,  Shimomura Iichiro (Department of Metabolic Medicine, Osaka University Graduate School of Medicine)
Material： Journal of Atherosclerosis and Thrombosis (Web)  (J Atheroscler Thromb (Web))
Volume： 26  Issue： 3  Page： 233-245(J-STAGE)  Publication year： 2019 
JST Material Number： U0153A  ISSN： 1880-3873  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： mass spectrometry ,...
Semi thesaurus term： CE-MS analysis

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Author keywords (3)： Metabolomics ,  Coronary artery disease ,  Diabetes

JST classification (2)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Cardiovascular system diseases  (GJ03000C)

Substance index (7)： α-Aminoisobutyric acid ,  3-Hydroxybutyric acid ,  Glucosamine ,  Creatine ,  Thymine ,  Hypoxanthine ,  Nonanoic acid

Reference (42)：

• 1) Morrish NJ, Wang SL, Stevens LK, Fuller JH, Keen H. Mortality and causes of death in the WHO multinational study of vascular disease in diabetes. Diabetologia 2001; 44(Suppl. 2): S14-21
• 2) Eckel RH, Kahn R, Robertson RM, Rizza RA. Preventing cardiovascular disease and diabetes: a call to action from the American Diabetes Association and the American Heart Association. Circulation 2006; 113: 2943-2946
• 3) Stephens JW, Ambler G, Vallance P, Betteridge DJ, Humphries SE, Hurel SJ. Cardiovascular risk and diabetes. Are the methods of risk prediction satisfactory? Eur J Cardiovasc Prev Rehabil 2004; 11: 521-528
• 4) Simmons RK, Coleman RI, Price HC, Holman RR, Khaw KT, Wareham NJ, Griffin SJ. Performance of the UK Prospective Diabetes Study risk engine and the Framingham risk equations in estimating cardiovascular disease in the EPIC- Norfolk Cohort. Diabetes Care 2009; 32: 708-713
• 5) Van Dieren S, Peelen LM, Nöthlings U, van der Schouw YT, Rutten GE, Spijkerman AM, van der A DL, Sluik D, Boeing H, Moons KG, Beulens JW. External validation of the UK Prospective Diabetes Study (UKPDS) risk engine in patients with type 2 diabetes. Diabetologia 2011; 54: 264-270

Terms in the title (7)： CE-MS分析 ,  糖尿病患者 ,  CAD ,  代謝産物 ,  同定 ,  パイロット ,  研究