Art

J-GLOBAL ID：201902288618878591   Reference number：19A1641018

Structural characterization of the N-terminal kinase-interacting domain of an Hsp90-cochaperone Cdc37 by CD and solution NMR spectroscopy

CD及び溶液NMR分光法によるHsp90-コシャペロンCdc37のN末端キナーゼ相互作用ドメインの構造特性化【JST・京大機械翻訳】

Author (7)： Ihama Futoshi (Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Shimoadachi, Sakyo-ku, Kyoto 606-8501, Japan) ,  Yamamoto Mami (Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Shimoadachi, Sakyo-ku, Kyoto 606-8501, Japan) ,  Kojima Chojiro (Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka 565-0871, Japan) ,  Fujiwara Toshimichi (Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka 565-0871, Japan) ,  Matsuzaki Katsumi (Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Shimoadachi, Sakyo-ku, Kyoto 606-8501, Japan) ,  Miyata Yoshihiko (Graduate School of Biostudies, Kyoto University, Kitashirakawa Oiwake-cho, Sakyo-ku, Kyoto 606-8502, Japan) ,  Hoshino Masaru (Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Shimoadachi, Sakyo-ku, Kyoto 606-8501, Japan)
Material： Biochimica et Biophysica Acta  (BBA. Biomembranes)
Volume： 1867  Issue： 9  Page： 813-820  Publication year： 2019 
JST Material Number： B0207A  ISSN： 0005-2728  CODEN： BBBMBS  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Cdc37 is a protein kinase-targ...

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Thesaurus term： binding site ,  phosphorylation ,  chaperone protein ,  conformational transition ,  *NMR ,  *interaction ,  protein kinase ,  alpha helix ,  *domain structure ,  *kinase ,  *amino terminal ,  *Cdc37 ,  *cochaperone ,  Signal Transduction
Semi thesaurus term： cellular signal transduction ,  残基 , 【Automatic Indexing@JST】

Author keywords (6)： Intrinsically disordered protein ,  Phosphorylation ,  Conformational change ,  Nuclear magnetic resonance ,  Chemical exchange ,  Circular dichroism

JST classification (2)： Enzyme in general  (EB09010D) ,  Proteins and peptides in general  (EB03010N)

Terms in the title (11)： Cd ,  溶液 ,  NMR分光法 ,  HSP90 ,  コシャペロン ,  Cdc37 ,  N末端 ,  キナーゼ ,  相互作用 ,  ドメイン ,  構造特性