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J-GLOBAL ID：202002212418008174   Reference number：20A1441172

Zinc-aggravated M1 microglia regulate astrocytic engulfment via P2×7 receptors

亜鉛で悪化したM1ミクログリアはP2→7受容体を介して星状細胞の貪食を調節する【JST・京大機械翻訳】

Author (14)： Hamada Tomoya (Department of Pediatrics, Kochi Medical School, Kochi University, Kohasu, Okoh-cho, Nankoku 783-8505, Japan) ,  Hamada Tomoya (Department of Pharmacology, Kochi Medical School, Kochi University, Kohasu, Okoh-cho, Nankoku 783-8505, Japan) ,  Aratake Takaaki (Department of Pharmacology, Kochi Medical School, Kochi University, Kohasu, Okoh-cho, Nankoku 783-8505, Japan) ,  Aratake Takaaki (Research Fellow of Japan Society for the Promotion of Science, Japan) ,  Higashi Youichirou (Department of Pharmacology, Kochi Medical School, Kochi University, Kohasu, Okoh-cho, Nankoku 783-8505, Japan) ,  Ueba Yusuke (Department of Neurosurgery, Kochi Medical School, Kochi University, Kohasu, Okoh-cho, Nankoku 783-8505, Japan) ,  Shimizu Takahiro (Department of Pharmacology, Kochi Medical School, Kochi University, Kohasu, Okoh-cho, Nankoku 783-8505, Japan) ,  Shimizu Shogo (Department of Pharmacology, Kochi Medical School, Kochi University, Kohasu, Okoh-cho, Nankoku 783-8505, Japan) ,  Yawata Toshio (Department of Neurosurgery, Kochi Medical School, Kochi University, Kohasu, Okoh-cho, Nankoku 783-8505, Japan) ,  Ueba Tetsuya (Department of Neurosurgery, Kochi Medical School, Kochi University, Kohasu, Okoh-cho, Nankoku 783-8505, Japan) ,  Nakamura Rina (Department of Pharmacology, Kochi Medical School, Kochi University, Kohasu, Okoh-cho, Nankoku 783-8505, Japan) ,  Akizawa Toshifumi (Department of Pharmacology, Kochi Medical School, Kochi University, Kohasu, Okoh-cho, Nankoku 783-8505, Japan) ,  Fujieda Mikiya (Department of Pediatrics, Kochi Medical School, Kochi University, Kohasu, Okoh-cho, Nankoku 783-8505, Japan) ,  Saito Motoaki (Department of Pharmacology, Kochi Medical School, Kochi University, Kohasu, Okoh-cho, Nankoku 783-8505, Japan)
Material： Journal of Trace Elements in Medicine and Biology  (J Trace Elem Med Biol)
Volume： 61  Page： Null  Publication year： 2020 
JST Material Number： T0779A  ISSN： 0946-672X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Glial cells such as astrocytes...

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Thesaurus term： *Zinc ,  pretreatment ,  Inflammation ,  chelating reagent ,  anti-inflammatory action ,  *receptor ,  *Phagocytosis ,  Central Nervous System ,  Phenotype ,  lipopolysaccharide ,  granular material ,  glia cell ,  *astrocyte ,  *microglia ,  Neuroprotection

Author keywords (4)： Astrocyte ,  Engulfing activity ,  Microglia ,  Zinc

JST classification (5)： Biological function  (EB03040U) ,  Central nervous system  (EJ12030F) ,  Basic neurology  (GN01020W) ,  Basic research of anti-inflammatory drugs  (GW15010T) ,  Cytokines  (EB08090G)

Terms in the title (7)： 亜鉛 ,  悪化 ,  ミクログリア ,  受容体 ,  星状細胞 ,  貪食 ,  調節