Art

J-GLOBAL ID：202002230044208066   Reference number：20A2193976

Tumor hypoxia regulates ganglioside GM3 synthase, which contributes to oxidative stress resistance in malignant melanoma

腫瘍低酸素は悪性黒色腫における酸化ストレス耐性に寄与するガングリオシドGM3シンターゼを調節する【JST・京大機械翻訳】

Author (10)： Shimizu Takuto (Laboratory of Biochemistry, School of Veterinary Medicine, Azabu University, Japan) ,  Nagane Masaki (Laboratory of Biochemistry, School of Veterinary Medicine, Azabu University, Japan) ,  Suzuki Mira (Laboratory of Biochemistry, School of Veterinary Medicine, Azabu University, Japan) ,  Yamauchi Akinori (Laboratory of Biochemistry, School of Veterinary Medicine, Azabu University, Japan) ,  Kato Kazuhiro (Laboratory of Biochemistry, School of Veterinary Medicine, Azabu University, Japan) ,  Kawashima Nagako (Department of Nephrology, Kitasato University School of Medicine, Japan) ,  Nemoto Yuki (Teaching Animal Hospital, Azabu University, Japan) ,  Maruo Takuya (Teaching Animal Hospital, Azabu University, Japan) ,  Kawakami Yasushi (Department of Life and Environmental Sciences, Azabu University, Japan) ,  Yamashita Tadashi (Laboratory of Biochemistry, School of Veterinary Medicine, Azabu University, Japan)
Material： Biochimica et Biophysica Acta  (BBA. Biomembranes)
Volume： 1864  Issue： 12  Page： Null  Publication year： 2020 
JST Material Number： B0207A  ISSN： 0005-2728  CODEN： BBBMBS  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Tumor hypoxia drastically chan...

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Thesaurus term： biosynthesis ,  *ganglioside ,  *tumor ,  phenotype ,  subunit ,  *oxygen deficiency ,  *malignant melanoma ,  cellular signal transduction ,  up-regulation ,  angiogenesis ,  apoptosis ,  *oxidative stress ,  lipid raft ,  *synthase ,  RNA interference

Author keywords (5)： Glycosphingolipids ,  Ganglioside GM3 ,  Hypoxia ,  Oxidative stress ,  Tumor microenvironment

JST classification (1)： Biological function  (EB05020M)

Terms in the title (8)： 腫瘍 ,  低酸素 ,  悪性黒色腫 ,  酸化 ,  ストレス耐性 ,  ガングリオシドGM3 ,  シンターゼ ,  調節