Art

J-GLOBAL ID：202002235294452422   Reference number：20A1175758

p63 is a cereblon substrate involved in thalidomide teratogenicity

p63はサリドマイド催奇形性に関与する小脳基質である【JST・京大機械翻訳】

Author (12)： Asatsuma-Okumura Tomoko (Department of Nanoparticle Translational Research, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan) ,  Ando Hideki (Department of Nanoparticle Translational Research, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan) ,  De Simone Marco (Department of Biosciences, Universita degli Studi di Milano, Milan, Italy) ,  Yamamoto Junichi (Department of Nanoparticle Translational Research, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan) ,  Sato Tomomi (Department of Nanoparticle Translational Research, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan) ,  Shimizu Nobuyuki (Department of Nanoparticle Translational Research, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan) ,  Asakawa Kazuhide (Department of Nanoparticle Translational Research, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan) ,  Yamaguchi Yuki (School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan) ,  Ito Takumi (Department of Nanoparticle Translational Research, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan) ,  Ito Takumi (PRESTO, JST, 4-1-8 Honcho, Kawaguchi, Japan) ,  Guerrini Luisa (Department of Biosciences, Universita degli Studi di Milano, Milan, Italy) ,  Handa Hiroshi (Department of Nanoparticle Translational Research, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan)
Material： Nature Chemical Biology  (Nat Chem Biol)
Volume： 15  Issue： 11  Page： 1077-1084  Publication year： 2019 
JST Material Number： W2213A  ISSN： 1552-4450  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: Cereblon (CRBN) is a...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=20A1175758&from=J-GLOBAL&jstjournalNo=W2213A") }}

Thesaurus term： auditory sense ,  *substrate(biochemistry) ,  substrate specificity ,  antitumor action ,  receptor ,  *cerebellum ,  pharmacological action ,  cochlea ,  complex(substance) ,  teratogenicity ,  analogical material ,  Danio rerio ,  p53 protein ,  aromatic carboxylic acid ,  immunotherapeutic drug ,  acid imide ,  polynuclear aromatic compound ,  dicarboxylic acid
Semi thesaurus term： アイソフォーム , 【Automatic Indexing@JST】

JST classification (4)： Receptors on cell membrane  (EF04030C) ,  Cell division and proliferation  (EF02020D) ,  Cell physiology in general  (EF02010S) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (1)： Thalidomide

Terms in the title (5)： p63 ,  サリドマイド ,  催奇形性 ,  小脳 ,  基質