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J-GLOBAL ID：202002244804014204   Reference number：20A0132737

A Validation Study of a New In Vitro Eye Irritation Test using the Reconstructed Human Corneal Epithelial Tissue, LabCyte CORNEA-MODEL24

再構成ヒト角膜上皮組織LabCyte CORNEA-Model24を用いる新たなin vitro眼刺激試験の検証研究

Author (19)： NAKAHARA Satoshi (Maruishilabo Corp., Osaka, JPN) ,  KOJIMA Hajime (National Inst. Health Sci., Tokyo, JPN) ,  OMORI Takashi (Kobe Univ. School of Medicine, Kobe, JPN) ,  YAMASHITA Aimi (Doshisha Univ., Kyoto, JPN) ,  ENDO Mai (Doshisha Univ., Kyoto, JPN) ,  SATAKE Maiko (Doshisha Univ., Kyoto, JPN) ,  NISHIURA Hideki (Nihon Kolmar Co., Ltd., Osaka, JPN) ,  SHINODA Shinsuke (Drug Safety Testing Center Co., Ltd., Saitama, JPN) ,  HAGIWARA Saori (Drug Safety Testing Center Co., Ltd., Saitama, JPN) ,  KASAHARA Toshihiko (Fujifilm Crop., Kanagawa, JPN) ,  TAHARA Haruna (Fujifilm Crop., Kanagawa, JPN) ,  YAMAMOTO Yusuke (Fujifilm Crop., Kanagawa, JPN) ,  IKEDA Hidefumi (Mandom Corp., Osaka, JPN) ,  YOSHITAKE Yuichiro (Oppen Cosmetics Co., Ltd., Shiga, JPN) ,  LEE Jeong Ik (Konkuk Univ., Seoul, KOR) ,  HAN Yuna (Konkuk Univ., Seoul, KOR) ,  LEE Soojung (Konkuk Univ., Seoul, KOR) ,  SUGAWARA Katsura (Japan Tissue Engineering Co., Ltd., Aichi, JPN) ,  KATOH Masakazu (Japan Tissue Engineering Co., Ltd., Aichi, JPN)
Material： Alternatives to Animal Testing and Experimentation  (AATEX)
Volume： 24  Issue： 1  Page： 11-23  Publication year： Oct. 31, 2019 
JST Material Number： L5507A  ISSN： 1344-0411  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *LabCyte CORNEA-Model24 ,...

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JST classification (3)： Bioassay  (EA03060N) ,  Toxicity of chemical substances in general  (GZ02010C) ,  Visual sense  (EJ13020B)

Reference (26)：

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• Alépée N., Adriaens E., Grandidier M.H., Meloni M., Nardelli L., Vinall C.J., Toner F., Roper C.S, Van Rompay A.R., Leblanc V., and Cotovio J., 2016b. Multi-laboratory evaluation of SkinEthic HCE test method for testing serious eye damage/eye irritation using solid chemicals and overall performance of the test method with regard to solid and liquid chemicals testing. Toxicol. In Vitro 31, 55-70.
• Christian M.S., and Diener R.M., 1996. Soaps and deergents, alternatives to animal eye irritation test. J. Am. Cell Toxicol. 15, 1-44.
• Cotovio, J., Grandidier, M.-H., Lelièvre, D., Bremond, C., Amsellem, C., Maloug, S., Ovigne, J.-M., Loisel-Joubert, S., Lee, A.V.D., Minondo, A.-M., Capallere, C., Bertino, B., Alépée, N., Tinois- Tessonneaud, E., Fraissinette, A.D.B., Meunier, J.-R., Leclaire, J., 2010. In vitro assessment of eye irritancy using the Reconstructed Human Corneal Epithelial SkinEthicTM. HCE model: Application to 435 substances from consumer products industry. Toxicol. In Vitro 24, 523-537.

Terms in the title (8)： 再構成 ,  ヒト ,  角膜上皮 ,  組織 ,  眼刺激 ,  試験 ,  検証 ,  研究