Art

J-GLOBAL ID：202002251016115802   Reference number：20A1940095

Report of the use of patient-derived xenograft models in the development of anticancer drugs in Japan

日本における抗癌剤の開発における患者由来異種移植モデルの使用報告

Author (12)： Tsumura Ryo (Division of Developmental Therapeutics, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Japan) ,  Koga Yoshikatsu (Department of Strategic Programs, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Japan) ,  Hamada Akinobu (Division of Molecular Pharmacology and Pharmacokinetics, National Cancer Center Research Institute, Tokyo, Japan) ,  Kuwata Takeshi (Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Japan) ,  Sasaki Hiroki (Department of Translational Oncology, Fundamental Innovative Oncology Core Center, National Cancer Center Research Institute, Tokyo, Japan) ,  Doi Toshihiko (Department of Experimental Therapeutics, National Cancer Center Hospital East, Kashiwa, Japan) ,  Aikawa Katsuji (Seeds Development Support Section, Translational Research Management Division, National Cancer Center Hospital East, Kashiwa, Japan) ,  Ohashi Akihiro (Division of Translational Genomics, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Japan) ,  Katano Ikumi (Central Institute for Experimental Animals, Kawasaki, Japan) ,  Ikarashi Yoshinori (Office of New Drug V, Pharmaceuticals and Medical Devices Agency, Tokyo, Japan) ,  Ito Mamoru (Central Institute for Experimental Animals, Kawasaki, Japan) ,  Ochiai Atsushi (Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 111  Issue： 9  Page： 3386-3394  Publication year： 2020 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： Mus musculus ,...
Semi thesaurus term： *drug development

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=20A1940095&from=J-GLOBAL&jstjournalNo=U0505A") }}

Author keywords (5)： animal model ,  drug development ,  patient-derived xenograft model ,  questionnaire ,  regulatory science

JST classification (2)： Research methods  (GV01020U) ,  Research and development  (GU01040N)

Terms in the title (7)： 日本 ,  抗癌剤 ,  開発 ,  患者 ,  異種移植 ,  モデル ,  報告