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J-GLOBAL ID：202002251067381358   Reference number：20A0200442

Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome

中心CENP-Aヌクレオソームを含む動原体三ヌクレオソームの低温EM構造【JST・京大機械翻訳】

Author (18)： Takizawa Yoshimasa (Laboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan) ,  Takizawa Yoshimasa (Molecular Cryo-Electron Microscopy Unit, Okinawa Institute of Science and Technology Graduate University, 1919-1 Tancha, Onna-son, Kunigami-gun, Okinawa 904-0495, Japan) ,  Ho Cheng-Han (Laboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan) ,  Ho Cheng-Han (Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan) ,  Tachiwana Hiroaki (Graduate School of Advanced Science & Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan) ,  Tachiwana Hiroaki (Department of Cancer Biology, The Cancer Institute of Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo 135-8550, Japan) ,  Matsunami Hideyuki (Molecular Cryo-Electron Microscopy Unit, Okinawa Institute of Science and Technology Graduate University, 1919-1 Tancha, Onna-son, Kunigami-gun, Okinawa 904-0495, Japan) ,  Kobayashi Wataru (Laboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan) ,  Kobayashi Wataru (Graduate School of Advanced Science & Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan) ,  Suzuki Midori (Graduate School of Advanced Science & Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan) ,  Arimura Yasuhiro (Laboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan) ,  Hori Tetsuya (Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Fukagawa Tatsuo (Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamada-oka, Suita, Osaka 565-0871, Japan) ,  Ohi Melanie D. (Life Science Institute, Cell & Developmental Biology, University of Michigan Medical School, 210 Washtenaw, Ann Arbor, MI 48109-2200, USA) ,  Wolf Matthias (Molecular Cryo-Electron Microscopy Unit, Okinawa Institute of Science and Technology Graduate University, 1919-1 Tancha, Onna-son, Kunigami-gun, Okinawa 904-0495, Japan) ,  Kurumizaka Hitoshi (Laboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan) ,  Kurumizaka Hitoshi (Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan) ,  Kurumizaka Hitoshi (Graduate School of Advanced Science & Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan)
Material： Structure
Volume： 28  Issue： 1  Page： 44-53.e4  Publication year： 2020 
JST Material Number： A1212A  ISSN： 0969-2126  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The histone H3 variant CENP-A ...

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Thesaurus term： targeting ,  reconstitution ,  Proteins ,  torsional deformation ,  higher order structure ,  *low temperature ,  chromatin ,  *nucleosome ,  robustness ,  three dimension ,  DNA ,  histone ,  condensation ,  cryoelectron microscope ,  *CENP-A

Author keywords (6)： centromere ,  CENP-A ,  chromatin ,  cryo-EM ,  nucleosome ,  histone variant

JST classification (2)： Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U)

Terms in the title (5)： CENP-A ,  ヌクレオソーム ,  動原体 ,  低温 ,  EM