Art

J-GLOBAL ID：202002253732900801   Reference number：20A0450813

Claudin-2 binding peptides, VPDSM and DSMKF, down-regulate claudin-2 expression and anticancer resistance in human lung adenocarcinoma A549 cells

クローディン-2結合ペプチド,VPDSMおよびDSMKFはヒト肺腺癌A549細胞におけるクラウジン-2発現および抗癌耐性を下方制御する【JST・京大機械翻訳】

Author (10)： Nasako Haruka (Laboratory of Biochemistry, Department of Biopharmaceutical Sciences, Gifu Pharmaceutical University, Gifu 501-1196, Japan) ,  Akizuki Risa (Laboratory of Biochemistry, Department of Biopharmaceutical Sciences, Gifu Pharmaceutical University, Gifu 501-1196, Japan) ,  Takashina Yui (Laboratory of Biochemistry, Department of Biopharmaceutical Sciences, Gifu Pharmaceutical University, Gifu 501-1196, Japan) ,  Ishikawa Yoshinobu (Department of Physical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka 422-8526, Japan) ,  Shinoda Takehiro (Laboratory for Protein Functional and Structural Biology, RIKEN Center for Biosystems Dynamics Research, Yokohama 230-0045, Japan) ,  Shirouzu Mikako (Laboratory for Protein Functional and Structural Biology, RIKEN Center for Biosystems Dynamics Research, Yokohama 230-0045, Japan) ,  Asai Tomohiro (Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka 422-8526, Japan) ,  Matsunaga Toshiyuki (Education Center of Green Pharmaceutical Sciences, Gifu Pharmaceutical University, Gifu 502-8585, Japan) ,  Endo Satoshi (Laboratory of Biochemistry, Department of Biopharmaceutical Sciences, Gifu Pharmaceutical University, Gifu 501-1196, Japan) ,  Ikari Akira (Laboratory of Biochemistry, Department of Biopharmaceutical Sciences, Gifu Pharmaceutical University, Gifu 501-1196, Japan)
Material： Biochimica et Biophysica Acta  (BBA. Biomembranes)
Volume： 1867  Issue： 4  Page： Null  Publication year： 2020 
JST Material Number： B0207A  ISSN： 0005-2728  CODEN： BBBMBS  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Claudin-2 (CLDN2), a tight jun...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=20A0450813&from=J-GLOBAL&jstjournalNo=B0207A") }}

Thesaurus term： mRNA ,  *peptide ,  adjuvant ,  sensitivity ,  three dimension ,  *A549 cell ,  lysosome ,  aggregation ,  adaptor protein ,  cytotoxicity ,  protein ,  chemical substance ,  *human(primates) ,  antitumor drug ,  *down-regulation

Author keywords (4)： Claudin ,  Lung adenocarcinoma ,  Chemoresistance ,  Short peptide

JST classification (5)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Transport of cell membrane  (EF04020R) ,  Cell physiology in general  (EF02010S) ,  Gene expression  (EC02040Q) ,  Biological function  (EB03040U)

Terms in the title (10)： クローディン-2 ,  ペプチド ,  ヒト ,  肺腺癌 ,  A549細胞 ,  クラウジン-2 ,  発現 ,  癌 ,  耐性 ,  下方制御