Art

J-GLOBAL ID：202002258920185804   Reference number：20A2155663

Deficiency of 3-hydroxybutyrate dehydrogenase (BDH1) in mice causes low ketone body levels and fatty liver during fasting

マウスにおける3-ヒドロキシブチラートデヒドロゲナーゼ(BDH1)の欠乏は絶食時の低ケトン体レベルおよび脂肪肝を引き起こす【JST・京大機械翻訳】

Author (19)： Otsuka Hiroki (Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu City, Japan) ,  Otsuka Hiroki (Department of Neonatology, Gifu Prefectural General Medical Center, Gifu City, Japan) ,  Kimura Takeshi (Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu City, Japan) ,  Ago Yasuhiko (Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu City, Japan) ,  Nakama Mina (Clinical Genetics Center, Gifu University Hospital, Gifu City, Japan) ,  Aoyama Yuka (Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu City, Japan) ,  Aoyama Yuka (Department of Biomedical Sciences, College of Life and Health Sciences, Education and Training Center of Medical Technology, Chubu University, Kasugai City, Japan) ,  Abdelkreem Elsayed (Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu City, Japan) ,  Abdelkreem Elsayed (Department of Pediatrics, Faculty of Medicine, Sohag University, Nasser City, Egypt) ,  Matsumoto Hideki (Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu City, Japan) ,  Ohnishi Hidenori (Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu City, Japan) ,  Sasai Hideo (Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu City, Japan) ,  Sasai Hideo (Clinical Genetics Center, Gifu University Hospital, Gifu City, Japan) ,  Osawa Masatake (Department of Regenerative Medicine and Applied Medical Sciences, Graduate School of Medicine, Gifu University, Gifu City, Japan) ,  Osawa Masatake (Gifu Center for Highly Advanced Integration of Nanosciences and Life Sciences (G-CHAIN), Gifu University, Gifu City, Japan) ,  Yamaguchi Seiji (Department of Pediatrics, Graduate School of Medicine, Shimane University, Izumo City, Japan) ,  Mitchell Grant A. (Division of Medical Genetics, Department of Pediatrics, CHU Sainte-Justine and Universite de Montreal, Montreal, Quebec, Canada) ,  Fukao Toshiyuki (Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu City, Japan) ,  Fukao Toshiyuki (Clinical Genetics Center, Gifu University Hospital, Gifu City, Japan)
Material： Journal of Inherited Metabolic Disease
Volume： 43  Issue： 5  Page： 960-968  Publication year： 2020 
JST Material Number： T0139A  ISSN： 0141-8955  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： d-3-Hydroxy-n-butyrate dehydro...

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Thesaurus term： energy balance ,  food ,  enzyme ,  *ketone ,  Heredity ,  lipid ,  *Fatty Liver ,  *Fasting ,  human ,  Mammalia ,  *ketone body ,  fertility (ratio) ,  wild type ,  *dehydrogenase ,  tolerability ,  Vertebrata

Author keywords (5)： 3-hydroxybutyrate dehydrogenase ,  CRISPR ,  fatty liver ,  ketone body ,  knockout mouse

JST classification (1)： Enzyme in general  (EB09010D)

Terms in the title (7)： マウス ,  3-ヒドロキシブチラート ,  デヒドロゲナーゼ ,  欠乏 ,  絶食 ,  ケトン体 ,  脂肪肝