Art

J-GLOBAL ID：202002263356842077   Reference number：20A1679432

Base editors for simultaneous introduction of C-to-T and A-to-G mutations

CからTおよびAからGの同時塩基置換を誘導する塩基エディター

Author (37)： SAKATA Rina C. (Synthetic Biology Div., Res. Center for Advanced Sci. and Technol., Univ. Tokyo, Tokyo, JPN) ,  ISHIGURO Soh (Synthetic Biology Div., Res. Center for Advanced Sci. and Technol., Univ. Tokyo, Tokyo, JPN) ,  MORI Hideto (Synthetic Biology Div., Res. Center for Advanced Sci. and Technol., Univ. Tokyo, Tokyo, JPN) ,  TANAKA Mamoru (Synthetic Biology Div., Res. Center for Advanced Sci. and Technol., Univ. Tokyo, Tokyo, JPN) ,  SEKI Motoaki (Synthetic Biology Div., Res. Center for Advanced Sci. and Technol., Univ. Tokyo, Tokyo, JPN) ,  MASUYAMA Nanami (Synthetic Biology Div., Res. Center for Advanced Sci. and Technol., Univ. Tokyo, Tokyo, JPN) ,  TOMITA Masaru (Synthetic Biology Div., Res. Center for Advanced Sci. and Technol., Univ. Tokyo, Tokyo, JPN) ,  YACHIE Nozomu (Synthetic Biology Div., Res. Center for Advanced Sci. and Technol., Univ. Tokyo, Tokyo, JPN) ,  SAKATA Rina C. (Coll. of Arts and Sci., Univ. Tokyo, Tokyo, JPN) ,  YACHIE Nozomu (Coll. of Arts and Sci., Univ. Tokyo, Tokyo, JPN) ,  ISHIGURO Soh (Inst. for Advanced Biosciences, Keio Univ., Tsuruoka, JPN) ,  MORI Hideto (Inst. for Advanced Biosciences, Keio Univ., Tsuruoka, JPN) ,  MASUYAMA Nanami (Inst. for Advanced Biosciences, Keio Univ., Tsuruoka, JPN) ,  ARAKAWA Kazuharu (Inst. for Advanced Biosciences, Keio Univ., Tsuruoka, JPN) ,  TOMITA Masaru (Inst. for Advanced Biosciences, Keio Univ., Tsuruoka, JPN) ,  YACHIE Nozomu (Inst. for Advanced Biosciences, Keio Univ., Tsuruoka, JPN) ,  ISHIGURO Soh (Graduate School of Media and Governance, Keio Univ., Fujisawa, JPN) ,  MORI Hideto (Graduate School of Media and Governance, Keio Univ., Fujisawa, JPN) ,  MASUYAMA Nanami (Graduate School of Media and Governance, Keio Univ., Fujisawa, JPN) ,  ARAKAWA Kazuharu (Graduate School of Media and Governance, Keio Univ., Fujisawa, JPN) ,  TOMITA Masaru (Graduate School of Media and Governance, Keio Univ., Fujisawa, JPN) ,  YACHIE Nozomu (Graduate School of Media and Governance, Keio Univ., Fujisawa, JPN) ,  TATSUNO Kenji (Genome Sci. Div., Res. Center for Advanced Sci. and Technol., Univ. Tokyo, Tokyo, JPN) ,  YAMAMOTO Shogo (Genome Sci. Div., Res. Center for Advanced Sci. and Technol., Univ. Tokyo, Tokyo, JPN) ,  ABURATANI Hiroyuki (Genome Sci. Div., Res. Center for Advanced Sci. and Technol., Univ. Tokyo, Tokyo, JPN) ,  UEDA Hiroki (Biological Data Sci. Div., Res. Center for Advanced Sci. and Technol., Univ. Tokyo, Tokyo, JPN) ,  NISHIDA Keiji (Engineering Biology Res. Center, Kobe Univ., Kobe, JPN) ,  KONDO Akihiko (Engineering Biology Res. Center, Kobe Univ., Kobe, JPN) ,  NISHIDA Keiji (Graduate School of Sci., Technol. and Innovation, Kobe Univ., Kobe, JPN) ,  KONDO Akihiko (Graduate School of Sci., Technol. and Innovation, Kobe Univ., Kobe, JPN) ,  NISHIMASU Hiroshi (Dep. of Biological Sci., School of Sci., Univ. Tokyo, Tokyo, JPN) ,  NUREKI Osamu (Dep. of Biological Sci., School of Sci., Univ. Tokyo, Tokyo, JPN) ,  YACHIE Nozomu (Dep. of Biological Sci., School of Sci., Univ. Tokyo, Tokyo, JPN) ,  ARAKAWA Kazuharu (Fac. of Environment and Information Studies, Keio Univ., Fujisawa, JPN) ,  TOMITA Masaru (Fac. of Environment and Information Studies, Keio Univ., Fujisawa, JPN) ,  KONDO Akihiko (Dep. of Chemical Sci. and Engineering, Graduate School of Engineering, Kobe Univ., Kobe, JPN) ,  YACHIE Nozomu (PRESTO, Japan Sci. and Technol. Agency (JST), Tokyo, JPN)
Material： Nature Biotechnology  (Nat Biotechnol)
Volume： 38  Issue： 7  Page： 865-869  Publication year： Jul. 2020 
JST Material Number： H0870A  ISSN： 1087-0156  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： DNA ,  RNA ,  Adenosine Deaminase ,  genome ,  editor ,  *base pair substitution ,  Cytosine Deaminase ,  Cas9 protein ,  nitrogen heterocyclic compound ,  urea compound
Semi thesaurus term： Cas9 , 【Automatic Indexing@JST】

JST classification (2)： Gene manipulation  (EC02050B) ,  Structure and chemistry of genes  (EC02020U)

Substance index (2)： Adenine ,  Cytosine

Terms in the title (3)： 塩基置換 ,  誘導 ,  塩基エディター