Art

J-GLOBAL ID：202002284689371611   Reference number：20A2065297

Successive cleavage of β-amyloid precursor protein by γ-secretase

γ-セクレターゼによるβ-アミロイド前駆体蛋白質の連続的切断【JST・京大機械翻訳】

Author (4)： Funamoto Satoru (Department of Neuropathology, Graduate School of Life and Medical Sciences, Doshisha University, Kyoto, Japan) ,  Tagami Shinji (Neuropsychiatry, Department of Integrated Medicine, Division of Internal Medicine, Osaka University Graduate School of Medicine, Suita, Japan) ,  Okochi Masayasu (Neuropsychiatry, Department of Integrated Medicine, Division of Internal Medicine, Osaka University Graduate School of Medicine, Suita, Japan) ,  Morishima-Kawashima Maho (Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan)
Material： Seminars in Cell & Developmental Biology  (Semin Cell Dev Biol)
Volume： 105  Page： 64-74  Publication year： 2020 
JST Material Number： T0944B  ISSN： 1084-9521  Document type： Article
Article type： 文献レビュー  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： γ-Secretase is a multimeric as...

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Thesaurus term： intermolecular interaction ,  enzyme ,  peptide ,  tripeptide ,  *precursor (substance) ,  proteolysis ,  multimer ,  targeting ,  Alzheimer Disease ,  pathogenesis ,  amyloid beta-protein ,  C-terminal side ,  *gamma-secretase ,  *secretase ,  amyloid beta 42 ,  Amyloid ,  glycoprotein ,  animal protein

Author keywords (6)： Amyloid β-protein ,  γ-Secretase ,  APP ,  Intramembrane proteolysis ,  Tripeptide ,  γ-Byproduct

JST classification (1)： Basic neurology  (GN01020W)

Terms in the title (4)： γ-セクレターゼ ,  β-アミロイド ,  前駆体 ,  蛋白質