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J-GLOBAL ID：202102216161216573   Reference number：21A0459180

Administration of FK506 from Late Stage of Disease Prolongs Survival of Human Prion-Inoculated Mice

疾患後期からのFK506投与は,ヒトプリオン接種マウスの生存を延長する【JST・京大機械翻訳】

Author (11)： Nakagaki Takehiro (Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan) ,  Ishibashi Daisuke (Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan) ,  Ishibashi Daisuke (Department of Immunological and Molecular Pharmacology, Faculty of Pharmaceutical Science, Fukuoka University, Fukuoka, Japan) ,  Mori Tsuyoshi (Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan) ,  Miyazaki Yukiko (Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan) ,  Takatsuki Hanae (Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan) ,  Tange Hiroya (Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan) ,  Taguchi Yuzuru (Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan) ,  Satoh Katsuya (Department of Locomotive Rehabilitation Science, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan) ,  Atarashi Ryuichiro (Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan) ,  Nishida Noriyuki (Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan)
Material： Neurotherapeutics
Volume： 17  Issue： 4  Page： 1850-1860  Publication year： 2020 
JST Material Number： W4806A  ISSN： 1933-7213  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: Human prion diseases...

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Thesaurus term： heredity ,  human(primates) ,  intraperitoneal administration ,  immunosuppressant ,  clinical trial ,  Rodentia ,  pathological state ,  *prion ,  pathogenesis ,  prion disease ,  microglia ,  prion protein ,  dementia
Semi thesaurus term： 神経膠症 ,  ノックインマウス , 【Automatic Indexing@JST】

Author keywords (5)： Sporadic Creutzfeldt-Jakob disease ,  FK506 ,  Microglia ,  Astrocyte ,  Spongiform change

JST classification (3)： Infectious diseases,parasitics diseases in general.  (GD01010H) ,  Nervous system diseases  (GN03000O) ,  Basic neurology  (GN01020W)

Terms in the title (8)： 疾患 ,  FK506 ,  投与 ,  ヒト ,  プリオン ,  接種 ,  マウス ,  生存