Art

J-GLOBAL ID：202102227181027559   Reference number：21A0217467

Characterization of Colibactin-Producing Escherichia coli Isolated from Japanese Patients with Colorectal Cancer

結腸直腸癌の日本人患者から分離したコリバクチン産生大腸菌のキャラクタリゼーション

Author (15)： Yoshikawa Yuko (School of Veterinary Medicine, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, Japan) ,  Yoshikawa Yuko (School of Food and Nutritional Sciences, University of Shizuoka, Japan) ,  Tsunematsu Yuta (Department of Pharmaceutical Sciences, University of Shizuoka, Japan) ,  Matsuzaki Nobuo (Department of Pharmaceutical Sciences, University of Shizuoka, Japan) ,  Hirayama Yuichiro (Department of Pharmaceutical Sciences, University of Shizuoka, Japan) ,  Higashiguchi Fumi (Department of Pharmaceutical Sciences, University of Shizuoka, Japan) ,  Sato Michio (Department of Pharmaceutical Sciences, University of Shizuoka, Japan) ,  Iwashita Yuji (Department of Tumor Pathology, Hamamatsu University School of Medicine, Japan) ,  Miyoshi Noriyuki (School of Food and Nutritional Sciences, University of Shizuoka, Japan) ,  Mutoh Michihiro (Epidemiology and Prevention Division, Center for Public Health Sciences, National Cancer Center, Japan) ,  Mutoh Michihiro (Department of Molecular-Targeting Cancer Prevention, Kyoto Prefectural University of Medicine, Japan) ,  Ishikawa Hideki (Department of Molecular-Targeting Cancer Prevention, Kyoto Prefectural University of Medicine, Japan) ,  Sugimura Haruhiko (Department of Tumor Pathology, Hamamatsu University School of Medicine, Japan) ,  Wakabayashi Keiji (Graduate Division of Nutritional and Environmental Sciences, University of Shizuoka, Japan) ,  Watanabe Kenji (Department of Pharmaceutical Sciences, University of Shizuoka, Japan)
Material： Japanese Journal of Infectious Diseases  (日本感染症雑誌)
Volume： 73  Issue： 6  Page： 437-442(J-STAGE)  Publication year： 2020 
JST Material Number： F0552A  ISSN： 1344-6304  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： コリバクチン産生菌 ,...

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Author keywords (4)： colibactin ,  commensal Escherichia coli ,  hemolytic activity ,  colorectal cancer

JST classification (3)： Infectious diseases,parasitics diseases in general.  (GD01010H) ,  Carcinogenic mechanisms and factors  (GE02020C) ,  Tumors(=neoplasms)of digestive system  (GH04000D)

Substance index (1)： Colibactin

Reference (35)：

• 1. Chumduri C, Gurumurthy RK, Zietlow R, et al. Subversion of host genome integrity by bacterial pathogens. Nat Rev Mol Cell Biol. 2016;17:659-73.
• 2. Faïs T, Delmas J, Barnich N, et al. Colibactin: more than a new bacterial toxin. Toxins. 2018;10:151.
• 3. Nougayrède JP, Homburg S, Taieb F, et al. Escherichia coli induces DNA double-strand breaks in eukaryotic cells. Science. 2006;313:848-51.
• 4. Cuevas-Ramos G, Petit CR, Marcq I, et al. Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells. Proc Natl Acad Sci U S A. 2010;107:11537-42.
• 5. Vizcaino MI, Crawford JM. The colibactin warhead crosslinks DNA. Nat Chem. 2015;7:411-7.

Terms in the title (5)： 結腸直腸癌 ,  日本人 ,  患者 ,  大腸菌 ,  キャラクタリゼーション