Art

J-GLOBAL ID：202102273453651158   Reference number：21A0372507

Engineering of Lipid Nanoparticles by the Multifunctionalization of the Surface with Amino Acid Derivatives for the Neutralization of a Target Toxic Peptide

標的毒性ペプチドの中和のためのアミノ酸誘導体による表面の多機能化による脂質ナノ粒子のエンジニアリング【JST・京大機械翻訳】

Author (10)： Koide Hiroyuki (Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, Shizuoka, 422-8526, Japan) ,  Hirano Satoshi (Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, Shizuoka, 422-8526, Japan) ,  Ide Takafumi (School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, Shizuoka, 422-8526, Japan) ,  Saito Kazuhiro (Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, Shizuoka, 422-8526, Japan) ,  Suzuki Hikaru (Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, Shizuoka, 422-8526, Japan) ,  Yasuno Go (Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, Shizuoka, 422-8526, Japan) ,  Hamashima Yoshitaka (School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, Shizuoka, 422-8526, Japan) ,  Yonezawa Sei (Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, Shizuoka, 422-8526, Japan) ,  Oku Naoto (Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, Shizuoka, 422-8526, Japan) ,  Asai Tomohiro (Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, Shizuoka, 422-8526, Japan)
Material： Advanced Functional Materials  (Adv Funct Mater)
Volume： 31  Issue： 3  Page： e2005641  Publication year： 2021 
JST Material Number： W1336A  ISSN： 1616-301X  CODEN： AFMDC6  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Protein affinity reagents (e.g...

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Thesaurus term： optimization ,  *amino acid ,  *peptide ,  conjugation ,  blood flow ,  antibody ,  *lipid ,  protein ,  hemolysis ,  affinity ,  cytotoxicity ,  drug delivery system ,  biocompatibility ,  *nano particle
Semi thesaurus term： 臨床応用 , 【Automatic Indexing@JST】

Author keywords (5)： amino acid ,  antibody ,  molecular recognition ,  nanoparticle ,  toxin

JST classification (2)： Medical materials  (GA05040H) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Terms in the title (8)： 標的 ,  毒性 ,  ペプチド ,  中和 ,  アミノ酸誘導体 ,  多機能 ,  脂質ナノ粒子 ,  エンジニアリング