Rchr
J-GLOBAL ID：202301007490874219
Update date: Sep. 24, 2024
Wada Mikako
ワダ ミカコ | Wada Mikako
Affiliation and department：
Job title：
Project Researcher
Research keywords (5)：
遺伝子治療
, アデノ随伴ウイルスベクター
, アデノウイルスベクター
, 性分化
, アフリカツメガエル
Research theme for competitive and other funds (3)：
- 2021 - 2024 Development of a hematopoietic stem cell-targeted lentiviral vector system
- 2018 - 2020 Genome-editing in hematopoietic cells with all-in-one HDAdV-CRISPR
- 2010 - 2015 sex differences regulated by W- and Y-sex chromosomes
Papers (9)：
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Makusu Tsutsui, Mikako Wada, Akihide Arima, Yuji Tsunekawa, Takako Sasaki, Kenji Sakamoto, Kazumichi Yokota, Yoshinobu Baba, Tomoji Kawai, Takashi Okada. Identifying Viral Vector Characteristics by Nanopore Sensing. ACS nano. 2024. 18. 24. 15695-15704
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Yae Kurosawa, Yuji Tsunekawa, Mikako Wada, Yuko Aizen, Yuko Nitahara-Kasahara, Takashi Okada. Purification of Adeno-Associated Viral Vector Serotype 9 Using Ceramic Hydroxyapatite Chromatography and its Analysis. Current protocols. 2024. 4. 6. e1068
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Kouhei Yoshida, Yuji Tsunekawa, Kento Kurihara, Kazuya Watanabe, Yuriko Makino-Manabe, Mikako Wada, Toru Tanaka, Teruhiko Ide, Takashi Okada. Engineering a highly durable adeno-associated virus receptor for analytical applications. Molecular therapy. Methods & clinical development. 2023. 31. 101157-101157
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Rimi Miyaoka, Yuji Tsunekawa, Yae Kurosawa, Takako Sasaki, Azusa Onodera, Kenji Sakamoto, Yuko Kakiuchi, Mikako Wada, Yuko Nitahara-Kasahara, Hiromi Hayashita-Kinoh, et al. Development of a novel purification method for AAV vectors using tangential flow filtration. Biotechnology and bioengineering. 2023. 120. 11. 3311-3321
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Mikako Wada, Naoya Uchida, Guillermo Posadas-Herrera, Hiromi Hayashita-Kinoh, Yuji Tsunekawa, Yukihiko Hirai, Takashi Okada. Large-scale purification of functional AAV particles packaging the full genome using short-term ultracentrifugation with a zonal rotor. Gene therapy. 2023. 30. 7-8. 641-648
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MISC (8)：
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和田美加子, 岡田尚巳. GMP Manufacturing for AAV Therapeutics. 医学のあゆみ. 2023. 285. 5. 317-320
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和田美加子, 奥島菜々子, 新田洋久, 岩長ゆずる, 早乙女彩, 栗原佳絵, 海老原康博, 三谷幸之介. CRISPR/Cas9による遺伝子修復治療法の確立に向けたSCID-X1モデルマーモセット造血幹前駆細胞でのゲノム編集. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
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中西晋也, 和田美加子, 田村啓, 三浦郁夫, 高松信彦, 伊藤道彦. ツメガエル属の生殖巣形成における雌デフォルト構造“mass-in-line”. 日本比較内分泌学会大会及びシンポジウムプログラム・講演要旨. 2018. 43rd
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和田美加子, 藤谷和子, 回渕修治, 田村啓, 高松信彦, 伊藤道彦. ツメガエル初期生殖巣形成におけるmass-in-line構造の雌雄化機構. 日本分子生物学会年会プログラム・要旨集(Web). 2016. 39th
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岡野則仁, 藤谷和子, 田村啓, 荻田悠作, 和田美加子, 高松信彦, 伊藤道彦. 生殖細胞運命・雄化に関わる転写因子DMRT1の天然変性領域とオーダー領域による転写活性化領域の分子進化. 日本分子生物学会年会プログラム・要旨集(Web). 2016. 39th
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Patents (1)：
Lectures and oral presentations (18)：
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Purification of the functional recombinant adeno-associated virus with zonal ultracentrifugation for manufacturing of gene therapy
(The 30th Annual Meeting of Japan Society of Gene and Cell Therapy 2024)
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Short-term and large-scale production of high-quality recombinant adeno-associated virus using a zonal ultracentrifugation
(The 27th Annual MeetingAmerican Society of Gene & Cell Therapy 2024)
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大規模製造に向けたゾーナル超遠心による 短時間高精度組換えアデノ随伴ウイルスベクター精製法の開発
(The 29th Annual Meeting of Japan Society of Gene and Cell Therapy 2023)
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GMP viral vector manufacturing for academia R&D
(The 29th Annual Meeting of Japan Society of Gene and Cell Therapy 2023)
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Large-scale production of high-quality recombinant adeno-associated virus using short-term zonal ultracentrifugation
(American Society of Gene & Cell Therapy 26th Annual Meeting 2023)
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Education (2)：
- 2012 - 2017 Kitasato University Graduate School of Science
- 2008 - 2012 Kitasato University School of Science Department of Biological Sciences
Work history (1)：
- 2017/04 - 2020/03 Saitama Medical University Research Center for Genomic Medicine Division of Gene Therapy
Awards (1)：
- 2024/05 - American Society of Gene & Cell Therapy's 27th Annual Meeting MERITORIOUS ABSTRACT TRAVEL AWARD
Association Membership(s) (1)：
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