Nagata Kazuhiro

ナガタカズヒロ | Nagata Kazuhiro

Affiliation and department：

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (3)：有機分子触媒反応 , 有機合成化学 , Heterocyclic Chemistry

Research theme for competitive and other funds (15)：

2012 - 2015 The development of antidiabetic and antithrombogenic drugs using marine natural products as lead compounds
2008 - 2010 Synthetic Studies of Isoquinoline and Indole Alkaloids Using Asymmetric Catalysis
2006 - 2007 Total Synthesis of Alkaloids usingAsymmetric Catalysts
2002 - 2003 Study of the chemical reactivity of nitric oxide and other related biological redicals
2000 - 2001 Development of the Selective NOS Inhibitors Based on Novel Reaction Mechanism

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Papers (57)：

Takuya Kanemitsu, Eisuke Ozasa, Yuria Murase, Susumu Sakaue, Michiko Miyazaki, Kazuhiro Nagata, Takashi Itoh. Asymmetric Construction of All-Carbon Quaternary Stereocenters via Organocatalytic α-Hydroxymethylation of Malonic Diesters Using Aqueous Formaldehyde. Asian Journal of Organic Chemistry. 2022. 11. 8
Kazuhiro Nagata, Chihiro Nakagawa, Wakana Yokoyama, Haruka Usui, Rikako Mochizuki, Takuya Kanemitsu, Michiko Miyazaki, Takashi Itoh. Synthesis and Catalytic Activities of 3-Decyl-β-proline for Michael Reactions in Water without an Organic Solvent. ACS Omega. 2021. 6. 30. 19642-19646
Yuki Odanaka, Takuya Kanemitsu, Kanako Iwasaki, Yukiko Mochizuki, Michiko Miyazaki, Kazuhiro Nagata, Masaru Kato, Takashi Itoh. Asymmetric Michael addition of malonic diesters to acrylates by phase-transfer catalysis toward the construction of quaternary stereogenic α-carbons. Tetrahedron. 2019. 75. 2. 209-219
Takuya Kanemitsu, Miho Sato, Miyuki Yoshida, Eisuke Ozasa, Michiko Miyazaki, Yuki Odanaka, Kazuhiro Nagata, Takashi Itoh. Enantioselective α-Benzoyloxylation of Malonic Diesters by Phase-Transfer Catalysis. Organic Letters. 2016. 18. 21. 5484-5487
Takuya Kanemitsu, Mizuho Inoue, Nono Yoshimura, Kazutoshi Yoneyama, Rie Watarai, Michiko Miyazaki, Yuki Odanaka, Kazuhiro Nagata, Takashi Itoh. A Concise One-Pot Organo- and Biocatalyzed Preparation of Enantiopure Hexahydrofuro[2,3-b]furan-3-ol: An Approach to the Synthesis of HIV Protease Inhibitors. European Journal of Organic Chemistry. 2016. 2016. 10. 1874-1880

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MISC (46)：

金光卓也, 小田中友紀, 宮崎倫子, 永田和弘, 伊藤喬. 相間移動触媒を用いたマロン酸ジエステルのα位四級不斉炭素構築法の開発. 反応と合成の進歩シンポジウム講演要旨集. 2018. 44th
永田和弘, 伊藤喬. バイオマーカー探索を指向した先端的薬学研究-その1-バイオマーカーとしての一酸化窒素(NO)およびその検出法. 昭和学士会雑誌. 2015. 75. 2. 168-176
伊藤喬, 永田和弘, 金光卓也, 宮崎倫子, 鳥居塚和生, 高松智, 福村基徳, 小池佑果. コショウからバニラを作る医薬品開発を指向した学部学生への化学系実習の試みと効果天然物化学から医薬品の合成へ. 日本薬学会年会要旨集. 2014. 134年会. 2. 174-174
Kazuhiro Nagata, Takashi Itoh, Keiko Kameoka, Michiko Miyazaki, Akio Ohsawa. Enantioselective synthesis of (S)-2,3,9,10,11-penta- methoxyhomoprotoberberine and (S)-O-methyl-kreysigine using an asymmetric addition to an isoquinoline ring. Heterocycles. 2001. 55. 12. 2269-2272
Takashi Itoh, Kazuhiro Nagata, Michiko Miyazaki, Keiko Kameoka, Akio Ohsawa. Asymmetric addition of nucleophiles to C-1 position of isoquinolines using (S)-alanine derivatives as chiral auxiliaries. Tetrahedron. 2001. 57. 42. 8827-8839

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Books (2)：

スタンダード薬学シリーズII 9 薬学演習 II. 基礎科学
東京化学同人 2021 ISBN:9784807917242
クライン有機化学問題の解き方 : 日本語版
東京化学同人 2020 ISBN:9784807909759

Education (4)：

- 1988 Toyama Medical and Pharmaceutical University
- 1988 Toyama Medical and Pharmaceutical University Graduate School, Division of Pharmaceutical Sciences
- 1986 Toyama Medical and Pharmaceutical University
- 1986 Toyama Medical and Pharmaceutical University Faculty of Pharmaceutical Science

Professional career (1)：

(BLANK) (Toyama Medical and Pharmaceutical University)

Work history (4)：

2007 - 現在 Showa University School of Pharmacy
2005 - 2007 Showa University School of Pharmacy
1996 - 2005 Showa University School of Pharmacy
1988 - 1995 Showa University School of Pharmacy

Association Membership(s) (2)：

THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN , 日本薬学会

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