文献

J-GLOBAL ID：201702277788131840   整理番号：17A0504344

アルツハイマー病の精神神経症状に対するYokukansan(抑肝散)の無作為化二重盲検プラセボ対照多施設共同試験

Randomized double-blind placebo-controlled multicenter trial of Yokukansan for neuropsychiatric symptoms in Alzheimer’s disease

著者 (34件)： Furukawa Katsutoshi (Department of Geriatrics and Gerontology, Division of Brain Sciences, Institute of Development, Aging and Cancer Tohoku University, Sendai, Japan) ,  Tomita Naoki (Department of Geriatrics and Gerontology, Division of Brain Sciences, Institute of Development, Aging and Cancer Tohoku University, Sendai, Japan) ,  Uematsu Daisuke (Uematsu Neurological Clinic, Saitama, Japan) ,  Okahara Kazunori (Keimei Memorial Hospital, Kunitomi, Japan) ,  Shimada Hiroyuki (Department of Geriatrics and Neurology, Osaka City University Graduate School of Medicine, Osaka, Japan) ,  Ikeda Masaki (Department of Neurology, Gunma University Graduate School of Medicine, Maebashi, Japan) ,  Matsui Toshifumi (National Hospital Organization Kurihama Medical and Addiction Center, Yokosuka, Japan) ,  Kozaki Koichi (Department of Geriatric Medicine, Kyorin University School of Medicine, Mitaka, Japan) ,  Fujii Masahiko (Yamagata Kousei Hospital, Yamagata, Japan) ,  Ogawa Tatsuji (Aoba Neurosurgical Clinic, Sendai, Japan) ,  Umegaki Hiroyuki (Department of Community Healthcare & Geriatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Urakami Katsuya (Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University, Yonago, Japan) ,  Nomura Hiroshi (Hiroshi Nomura Neurology Clinic, Sendai, Japan) ,  Kobayashi Naoto (Azuma Street Clinic, Fukushima, Japan) ,  Nakanishi Aki (Department of Neurology and Psychiatry, Osaka City Kousaiin Hospital, Suita, Japan) ,  Washimi Yukihiro (Department of Cognitive Disorders, National Center for Geriatrics and Gerontology, Obu, Japan) ,  Yonezawa Hisashi (Department of Neurology, Iwate Medical University, Morioka, Japan) ,  Takahashi Satoshi (Department of Neurology, Iwate Medical University, Morioka, Japan) ,  Kubota Masaharu (Kusakabe Memorial Hospital, Yamanashi, Japan) ,  Wakutani Yosuke (Neurology, Kurashiki Heisei Hospital, Kurashiki, Japan) ,  Ito Daisuke (Department of Neurology, School of Medicine, Keio University, Tokyo, Japan) ,  Sasaki Takahiro (Department of Neurology, School of Medicine, Saitama Medical University, Moroyama, Japan) ,  Matsubara Etsuro (Department of Neurology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, Yufu, Japan) ,  Une Kaori (Department of Geriatrics and Gerontology, Division of Brain Sciences, Institute of Development, Aging and Cancer Tohoku University, Sendai, Japan) ,  Ishiki Aiko (Department of Geriatrics and Gerontology, Division of Brain Sciences, Institute of Development, Aging and Cancer Tohoku University, Sendai, Japan) ,  Yahagi Yukie (Clinical Research, Innovation and Education Center, Tohoku University Hospital, Sendai, Japan) ,  Shoji Mikio (Department of Neurology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, Yufu, Japan) ,  Sato Hiroyasu (Clinical Research, Innovation and Education Center, Tohoku University Hospital, Sendai, Japan) ,  Terayama Yasuo (Department of Neurology, Iwate Medical University, Morioka, Japan) ,  Kuzuya Masafumi (Department of Community Healthcare & Geriatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan) ,  Araki Nobuo (Department of Neurology, School of Medicine, Saitama Medical University, Moroyama, Japan) ,  Kodama Manabu (Kodama Hospital, Ishinomaki, Japan) ,  Yamaguchi Takuhiro (Clinical Research, Innovation and Education Center, Tohoku University Hospital, Sendai, Japan) ,  Arai Hiroyuki (Department of Geriatrics and Gerontology, Division of Brain Sciences, Institute of Development, Aging and Cancer Tohoku University, Sendai, Japan)
資料名： Geriatrics & Gerontology International  (Geriatrics & Gerontology International)
巻： 17  号： 2  ページ： 211-218  発行年： 2017年02月 
JST資料番号： W1574A  ISSN： 1444-1586  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： アメリカ合衆国 (USA)  言語： 英語 (EN)

抄録/ポイント： 目的:伝統的な漢方薬であるYokukansan(YKS)は,...

シソーラス用語： ヒト ,...
準シソーラス用語： MMSE ,...

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著者キーワード (5件)： Alzheimer’s disease ,  behavioral and psychological symptoms of dementia ,  Kampo medicine ,  Neuropsychiatric Inventory Brief Questionnaire Form ,  Yokukansan

分類 (2件)： 神経系疾患の薬物療法  (GN05020Y) ,  生薬の臨床への応用  (GX06030U)

引用文献 (26件)：

• Finkel SI, Costa e Silva J, Cohen G, Miller S, Sartorius N. Behavioral and psychological signs and symptoms of dementia: a consensus statement on current knowledge and implications for research and treatment. Int Psychogeriatr 1996; 8 (Suppl 3): 497-500.
• Lyketsos CG, Steinberg M, Tschanz JT, Norton MC, Steffens DC, Breitner JC. Mental and behavioral disturbances in dementia: findings from the cache county study on memory in aging. Am J Psychiatry 2000; 157: 708-714.
• Ferri CP, Ames D, Prince M. Behavioral and psychological symptoms of dementia in developing countries. Int Psychogeriatr 2004; 16: 441-459.
• Steele C, Rovner B, Chase GA, Folstein M. Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease. Am J Psychiatry 1990; 147: 1049-1051.
• Coen RF, Swanwick GR, O'Boyle CA, Coakley D. Behaviour disturbance and other predictors of carer burden in Alzheimer's disease. Int J Geriatr Psychiatry 1997; 12: 331-336.

タイトルに関連する用語 (7件)： アルツハイマー ,  精神神経症状 ,  抑肝散 ,  二重盲検 ,  プラセボ ,  対照 ,  多施設共同試験