村山 幸一

• 医学系研究科  助教

• Study of Protein Structure and hydration by molecular spectroscopy
• Non-destructive measurement by Near-Infrared Spectroscopy
• Study of Protein Structure and its hydration by Molecular Spectroscopy
• 分子分光法によるタンパク質構造と水和の研究
• 分子分光法によるタンパク質の構造と水和の研究
近赤外分光法による非破壊計測

• Tomoyoshi Terada, Satoshi Nunomura, Toshibumi Shimokawa, Koichi Murayama, Seiichi Era, Naomi Kondo, Chisei Ra. Fc epsilon RI-induced mast cell cytokine production critically involves an aspartic acid residue (D234) in the C-terminal intracellular domain of the Fc epsilon RI beta chain. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2011. 410. 4. 744-748
• Koichi Murayama, Masashi Sonoyama, Tomoyoshi Terada, Yasunori Yokoyama, Masayuki Nara, Mihoko Tomida, Sadayuki Matsuda. Bisphenol A Weakens Calcium Binding Affinity of Sites III and IV in C-Terminal Domain of Bovine Brain Calmodulin. CHEMISTRY LETTERS. 2009. 38. 11. 1062-1063
• I. Iwai, K. Ikuta, K. Murayama, T. Hirao. Change in optical properties of stratum corneum induced by protein carbonylation in vitro. International Journal of Cosmetic Science. 2008. 30. 1. 41-46
• Bo Yuan, Koichi Murayama, Huiming Yan. Study of thermal dynamics of defatted bovine serum albumin in D2O solution by Fourier transform infrared spectra and evolving factor analysis. APPLIED SPECTROSCOPY. 2007. 61. 9. 921-927
• Bo Yuan, Koichi Murayama. Capillary method for measuring near-infrared spectra of microlitre volume liquids. JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE A. 2007. 8. 2. 171-175

もっと見る

• Koichi Murayama, Koichi Murayama, Yukihiro Ozaki. Two-dimensional near-IR correlation spectroscopy study of molten globule-like state of ovalbumin in acidic pH region: Simultaneous changes in hydration and secondary structure. Biopolymers - Biospectroscopy Section. 2016. 67. 394-405
• Koichi Murayama, Masashi Sonoyama, Sadayuki Matsuda. Strong Interaction of Bovine Brain Calmodulin with Bisphenol A: Effects on Secondary Structure, Conformation, Ca2+-Binding Affinity, Gibbs Energy, and Domain Cooperativity. BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN. 2015. 88. 6. 880-887
• Tomoyoshi Terada, Tomoyoshi Terada, Satoshi Nunomura, Toshibumi Shimokawa, Koichi Murayama, Seiichi Era, Naomi Kondo, Chisei Ra. FcεRI-induced mast cell cytokine production critically involves an aspartic acid residue (D234) in the C-terminal intracellular domain of the FcεRIβ chain. Biochemical and Biophysical Research Communications. 2011. 410. 4. 744-748
• Koichi Murayama, Masashi Sonoyama, Tomoyoshi Terada, Yasunori Yokoyama, Masayuki Nara, Mihoko Tomida, Sadayuki Matsuda. Bisphenol A Weakens Calcium Binding Affinity of Sites III and IV in C-Terminal Domain of Bovine Brain Calmodulin. CHEMISTRY LETTERS. 2009. 38. 11. 1062-1063
• I. Iwai, K. Ikuta, K. Murayama, T. Hirao. Change in optical properties of stratum corneum induced by protein carbonylation in vitro. International Journal of Cosmetic Science. 2008. 30. 1. 41-46

もっと見る

• 可視光及び/又は近赤外光を用いた乳房炎の有無を診断する方法及び装置

• 構造解析のための分子スペクトル分析法
  丸善 2003
• Near-Infrared Spectroscopy and Chemometrics Studies of Proteins in Aqueous Solutions: from Quantitative Analysis to Structural Studies
  CLUES(Bologna) 2003
• Infrared and Raman Spectroscopy and Chemometrics of Biological Materials(共著)
  Infrared and Raman Spectroscopy of Biological Materials, Marcel Dekker 2000

• Gibbs energies of secondary structures for a-Chymotrypsinogen A investigated by FT-IR spectroscopy
  (第50回日本生物物理学会年会 2012)
• 33. カルモデュリンとビスフェノールAの相互作用の考察
  (第11回日本蛋白質科学会年会 2011)
• 32. 等温カロリメトリー法によるカルモデュリンとビスフェノールAの相互作用に関する考察
  (環境ホルモン学会第13回研究発表会 2010)
• 31. カルモデュリンのカルシウム結合能と構造におけるビスフェノールAの影響
  (第10回日本蛋白質科学会年会 2010)
• 30. カルモジュリン-ビスフェノールA相互作用によるカルシウム結合能の減弱
  (環境ホルモン学会第12回研究発表会 2009)

もっと見る

• Study of Structure Changes of Protein in Porcine Stratum Corneum induced by Carbonylation
  2003 -
• 皮膚酸化タンパクの構造解析に関する研究
  2003 -

• 理学博士 (関西学院大学)

• 2012 - 岐阜大学 医学(系)研究科(研究院) 助教
• 岐阜大学 大学院医学研究科 分子生理学教室 助手

• 2003 - The Biophysical Society of Japan Editorial Board of Chubu Area in Japan
• 2003 - 国際近赤外分光学会 Council member
• 2003 - 日本生物物理学会 地区編集委員
• 2001 - Protein Science Society of Japan Member
• 2001 - The Biophysical Society of Japan Member
1999 - International Symposium on Two-Dimensional Correlation Spectroscopy, Local Organizing Committee
1996 - The Chemical Society of Japan Member
1996 - The Japan Society for Analytical Chemistry Member

• 2003 - Best Poster Award in 19th Symposium on Non-destructive Measurement Technology
• 2003 - 第19回非破壊計測シンポジウムベストポスター賞
• 2002 - NIR Advance Award
• 2002 - NIR Advance Award

環境ホルモン学会 ,  日本蛋白質科学会 ,  International Symposium on Two-Dimensional Correlation Spectroscopy. ,  Protein Science Society of Japan ,  The Biophysical Society of Japan ,  The Chemical Society of Japan ,  The Japan Society for Analytical Chemistry ,  国際近赤外分光学会 ,  蛋白質科学会 ,  日本生物物理学会 ,  日本化学会 ,  日本分析化学会