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J-GLOBAL ID：200901001463848070 Update date: Mar. 26, 2025

Kudou Takashi

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Affiliation and department：
Homepage URL (1)： https://mentalhealthpromotion-osaka-u.org/index.html

Research field (1)： Psychiatry

Research theme for competitive and other funds (47)：

2022 - 2025 Establishment of ultra-early Alzheimer's disease marker using plasma nerve-derived exosomes
2020 - 2023 プロテアソーム・トレランスを基盤とした認知症治療薬開発の研究
2018 - 2021 ヒト脳由来エクソソームを利用した認知症患者を層別化する手法の開発研究
2017 - 2019 家庭内コミュニケーションの活性化により精神疾患患者の症状改善を促す情報環境の構築
2017 - 2019 自覚的記憶障害者の精神症状の評価とBPSD予防法の検討

2017 - 2019 レム睡眠行動障害からレビー小体病の進展機構解明における包括的バイオマーカーの検討

2017 - 2019 発達障害・精神疾患を有する大学生不登校の実態および支援の現状と課題

2017 - 2019 エクソサイトのメカニズムの解明とそのアルツハイマー病治療への応用

2017 - 2019 糖尿病MCI患者のアルツハイマー病移行を抑止する糖尿病治療法の検討

2016 - 2018 精神療法に関するエビデンスの集積

2016 - 2018 アルツハイマー病におけるシグマ1受容体の関与とそれに基づいた治療法開発の研究

2014 - 2017 Research on information technology to support reducing stress of family caregivers of depressed patients

2013 - 2016 抗精神病薬により引き起こされるメタボリック症候群様症状の新たな生物学的機序の解明

2013 - 2016 Tactics of integrative medicine for posttraumatic residual disability by wide-scale disaster

2012 - 2016 The study on prediction of the operation on idiopathic normal pressure hydrocephalus

2012 - 2015 The analysis of neurodegenerative processes and changes of protein interaction of tau by mutation.

2012 - 2015 Pathogenesis of tauopathies in terms of protein quality control mechanism

2012 - 2015 The analysis of regulatory mechanisms of degradation/aggregation of abnormally accumulated protein in fontotemporal dementia brain.

2012 - 2014 Information Support for Caregivers of Depressed Individuals

2009 - 2011 The investigating the molecular mechanisms of cognitive impairment due to cancer chemotherapy and its prevention

2009 - 2011 The mechanisms of aggregation, accumulation and degradation of the genetically causative protein related to familial dementia diseases

2008 - 2010 Anti-inflammatory effects on amyloid vaccination therapy by NSAID : a development of Alzheimer disease therapy

2008 - 2010 Application of an ER chaperone inducer for Alzheimer disease

2007 - 2008 Involvement of protein s coded by causative genes for familial dementia and ubiquitin system in neurodegenerative mechanisms

2006 - 2007 The mechanisms of anti-Alzheimer dicaam effects by NSAIDs

2005 - 2006 Implication of ER stress in amyloid production and its application for therapeutic approach

2005 - 2006 Analysis of sequential endoproteolytic process of beta-APP to establish novel therapeutic interventions

2004 - 2005 Study on interaction between apoptosis inhibitory protein and tau protein, and its implication on neurodegeneration

2003 - 2004 Molecular mechanism of endoplasmic reticulum stress and Alzheimer disease

2003 - 2004 Neurodegenerative mechanism on ribotoxic stress and apoptosis

2003 - 2004 Study about apoptosis effect of FAD mutant

2002 - 2003 Mechanism of the nerve cell death accompanied with tau protein phosphorylation in tauopathy

2002 - 2003 Modification of genetic expression by intoronic microsatellite in risk genes of Alzheimer's disease

2001 - 2002 Involvement of endoplasmic stress responses in Alzheimer disease

2001 - 2002 The effects of repetitive transcranial magnetic stimulation on neurogenesis

2001 - 2002 Oxidative stress mechanisms related to ribotoxic stress and endoplasmic reticulum stress

2000 - 2001 アルミニウムとアルツハイマー病発症機構との因果関係に関する研究

2000 - 2000 アルツハイマー病の神経細胞変成機序とERストレスの研究

1999 - 2000 Cloning for presenilin cleaving enzyme

1999 - 2000 Study of neurofilament phosphorylation in long-term potentiation of hlppocampus

1997 - 2000 Animal Model for Evaluation of Druge on Therapeutics of Alzheimer Disease

1997 - 1998 Study of disfunctions of axons and abnormal phosphorylation of neurofilament in Alzheimer barins

1997 - 1998 Relationship between function of presenilin 1 and abnormal phosphorylation of tau

1996 - 1996 膜蛋白(S182蛋白)の変化とアルツハイマー病の病態について

1996 - 1996 慢性頭部衝撃による細胞骨格蛋白の異常リン酸化と神経変性機序に関する研究-アルツハイマー病の危険因子としての機械的軸索障害の検討-

1994 - 1995 Development of the animal model for Alzhcimer disease

Study on Pathogenesis of Alzheimer disease

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Papers (308)：

Chisaki Ishibashi, Kaori Nakanishi, Makoto Nishida, Haruki Shinomiya, Maki Shinzawa, Daisuke Kanayama, Ryohei Yamamoto, Takashi Kudo, Izumi Nagatomo, Keiko Yamauchi-Takihara. Myostatin as a plausible biomarker for early stage of sarcopenic obesity. Scientific reports. 2024. 14. 1. 28629-28629
金山大祐, 村井教子, 姫ヶ迫由美, 川村淳子, 梅野有希, 熊谷一代, 丸谷典子, 金井講治, 鐘本英輝, 山本陵平, et al. コロナ禍前後での精神科受診動向の変化について. 全国大学保健管理研究集会プログラム・抄録集. 2024. 62回. 82-82
大藏裕平, 佐竹祐人, 末廣聖, 梅田寿美代, 繁信和恵, 工藤喬, 鈴木由貴, 高橋励, 森悦朗, 橋本衛, et al. Lecanemab One Osaka Project LooPの取り組みについて. Dementia Japan. 2024. 38. 4. 684-684
Kazuhiro Shidara, Hiroki Tanaka, Hiroyoshi Adachi, Daisuke Kanayama, Takashi Kudo, Satoshi Nakamura. Adapting the Number of Questions Based on Detected Psychological Distress for Cognitive Behavioral Therapy With an Embodied Conversational Agent: Comparative Study. JMIR Formative Research. 2024. 8. e50056-e50056
熊谷一代, 金山大祐, 村井教子, 姫ヶ迫由美, 金井講治, 足立浩祥, 工藤喬. コロナ禍前後での精神科受診行動の変化について診断情報からの解析. CAMPUS HEALTH. 2024. 61. 1. 207-208

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MISC (198)：

大藏裕平, 佐竹祐人, 末廣聖, 梅田寿美代, 繁信和恵, 繁信和恵, 工藤喬, 鈴木由貴, 高橋励, 森悦朗, et al. Lecanemab One Osaka Project:LooPの取り組みについて. Dementia Japan. 2024. 38. 4
設樂一碩, 田中宏季, 足立浩祥, 金山大祐, 阪上由香子, 工藤喬, 中村哲. An Analysis of Questions to Evaluate an Automatic Thought in Cognitive Behavior Therapy with a Virtual Agent. 人工知能学会全国大会(Web). 2022. 36th
工藤喬. ウィズコロナの産業精神保健. 産業精神保健. 2021. 29. 3. 191-193
設樂一碩, 田中宏季, 足立浩祥, 金山大祐, 阪上由香子, 工藤喬, 中村哲. Identification of Automatic Thoughts in Cognitive Restructuring with a Virtual Agent. 人工知能学会全国大会(Web). 2021. 35th
工藤喬, 赤嶺祥真, 柳田寛太, 丸谷典子, 金山大祐. タウオパシーの成因と病態タウとエクソソーム. Dementia Japan. 2019. 33. 4. 485-485

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Books (8)：

Practical Pharmacology for Alzheimer’s Disease
Springer 2016
100 Papers Selection ANNUAL REPORT OF OSAKA UNIVERSITY-Academic Achievement-/2007-2008
Osaka University 2009
Biological markers for differential diagnosis of Alzheimer's disease and related disorders
Neuroscientific Basis of Dementia Birkhauser Verlag Basel 2001
Impairment of response to ER stress in presenilin 1 mutant
Neuroscientific Basis of Dementia Birkhauser Verlag Basel 2001
Biological markers for differential diagnosis of Alzheimer's disease and related disorders
Neuroscientific Basis of Dementia Birkhauser Verlag Basel 2001

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Lectures and oral presentations (5)：

認知症の血漿バイオマーカー
(第117回日本精神神経学会学術総会 2021)
精神神経疾患における血液バイオマーカーの可能性
(第117回日本精神神経学会学術総会 2021)
血液中脳由来エクソソームの認知症バイオマーカーとしての可能性
(第39回日本認知症学会学術集会 2020)
Blood biomarkers for dementia
(第63回日本神経化学会 2020)
Pathological significance of neuron-derived EVs in Alzheimer's disease and its potential as biomarkers
(The Alzheimer’s Association International Conference 2020)

Education (4)：

- 1991 Osaka University
- 1991 Osaka University Graduate School, Division of Medicine
- 1986 Osaka Medical College Faculty of Medicine Division of Medicine
- 1986 Osaka Medical College Faculty of Medicine

Professional career (1)：

(BLANK) (Osaka University)

Work history (8)：

2013 - 現在大阪大学キャンパスライフ健康支援センター教授
2001 - 2013 Osaka University
2000 - 2001 : 大阪大学講師
2000 - 2001 : Osaka University, Instructor
1995 - 2000 : 大阪大学助手

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Committee career (4)：

- 現在日本認知療法・認知行動療法学会監事
- 現在日本神経化学会理事
- 現在日本老年精神医学会理事
- 現在日本精神神経学会代議員

Association Membership(s) (8)：

日本精神薬理学会 , Japanese Society of Mood Disorders , THE JAPANESE ASSOCIATION FOR COGNITIVE THERAPY , JAPAN SOCIETY FOR DEMENTIA RESEARCH , Society of Neuroscience , 日本神経化学会 , 日本老年精神医学会 , 日本精神神経学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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