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J-GLOBAL ID：200901002375944058   Update date: Nov. 21, 2024

Kawashima Nobuyuki

カワシマ ノブユキ | Kawashima Nobuyuki
Affiliation and department：
Institute of Science Tokyo Department of Pulp Biology and Endodontics, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences,

About Institute of Science Tokyo Department of Pulp Biology and Endodontics, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences,


Job title： Associate Professor
Research field  (1)： Conservative dentistry and endodontics
Research keywords  (2)： 歯内治療学 ,  Pulp Biology and Endodontics
Research theme for competitive and other funds  (33)：
  • 2022 - 2025 低酸素特異的転写調節因子HIF1αが誘導する歯髄組織特異的硬組織誘導のメカニズム
  • 2021 - 2024 Investigation of a new therapy for auto-transplantation of developing teeth with NF-kB decoy ODN
  • 2021 - 2024 硬組織誘導能と炎症制御能を具備する新規直接覆髄材の開発とその臨床応用への展望
  • 2020 - 2023 粒子形状を制御した複合酸化物による新規歯内療法用セメントの開発と生体機能性付与
  • 2019 - 2022 Establishment of bacteriological examination method for diagnosing healing endodontic periodontal lesions
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Papers (43)：
  • Yadanar Su Phyo, Kentaro Hashimoto, Nobuyuki Kawashima, Masashi Kuramoto, Takashi Okiji. Evaluation of the cytocompatibility of methacrylate resin-based root canal sealers with osteoblast-like cells. Dental Materials Journal. 2021. 40. 4. 942-948
  • M. Kuramoto, N. Kawashima, K. Tazawa, K. Nara, M. Fujii, S. Noda, K. Hashimoto, K. Nozaki, T. Okiji. Mineral trioxide aggregate suppresses pro-inflammatory cytokine expression via the calcineurin/nuclear factor of activated T cells/early growth response 2 pathway in lipopolysaccharide-stimulated macrophages. International Endodontic Journal. 2020. 53. 12. 1653-1665
  • Kento Tazawa, Nobuyuki Kawashima, Masashi Kuramoto, Sonoko Noda, Mayuko Fujii, Keisuke Nara, Kentaro Hashimoto, Takashi Okiji. Transient Receptor Potential Ankyrin 1 Is Up-Regulated in Response to Lipopolysaccharide via P38/Mitogen-Activated Protein Kinase in Dental Pulp Cells and Promotes Mineralization. American Journal of Pathology. 2020. 190. 12. 2417-2426
  • Nobuyuki Kawashima, Kentaro Hashimoto, Masashi Kuramoto, Alamuddin Bakhit, Yasumiko Wakabayashi, Takashi Okiji. A Novel Bioactive Endodontic Sealer Containing Surface-Reaction-Type Prereacted Glass-Ionomer Filler Induces Osteoblast Differentiation. Materials (Basel, Switzerland). 2020. 13. 20
  • Nobuyuki Kawashima, Kentaro Hashimoto, Masashi Kuramoto, Alamuddin Bakhit, Yasumiko Wakabayashi, Takashi Okiji. A novel bioactive endodontic sealer containing surface-reaction-type prereacted glass-ionomer filler induces osteoblast differentiation. Materials. 2020. 13. 20. 1-10
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MISC (89)：
  • 小林 宏明, 川島 伸之, 須藤 毅顕, 加納 千博, 三神 亮, 片桐 さやか, 竹内 康雄, 岩田 隆紀. 治癒する歯周歯内病変を診断するための細菌学的検索. 日本歯周病学会会誌. 2020. 62. 秋季特別. 123-123
  • Sonoko Noda, Nobuyuki Kawashima, Mioko Yamamoto, Kentaro Hashimoto, Keisuke Nara, Ichiro Sekiya, Takashi Okiji. Effect of cell culture density on dental pulp-derived mesenchymal stem cells with reference to osteogenic differentiation. Scientific Reports. 2019. 9
  • Keisuke Nara, Nobuyuki Kawashima, Sonoko Noda, Mayuko Fujii, Kentaro Hashimoto, Kento Tazawa, Takashi Okiji. Anti-inflammatory roles of microRNA 21 in lipopolysaccharide-stimulated human dental pulp cells. Journal of Cellular Physiology. 2019. 234. 21331-21341
  • Mayuko Fujii, Nobuyuki Kawashima, Kento Tazawa, Kentaro Hashimoto, Keisuke Nara, Sonoko Noda, Masashi Kuramoto, Shion Orikasa, Shigenori Nagai, Takashi Okiji. HIF1α inhibits LPS-mediated induction of IL-6 synthesis via SOCS3-dependent CEBPβ suppression in human dental pulp cells. Biochemical and Biophysical Research Communications. 2019
  • Nobuyuki Kawashima, Takashi Okiji. Odontoblasts: Specialized hard-tissue-forming cells in the dentin-pulp complex. CONGENITAL ANOMALIES. 2016. 56. 4. 144-153
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Books (13)：
  • Dendritic Cells and Macrophages in the Pathologenesis of Periapical Lesions:A Phenotypic and Ultrastructural Analysis (coauther)
    Proceedings of the International Conference on Dentin/Pulp Complex 2001, Quintessence Publishing Co.,Ltd. 2002
  • 歯髄における免疫組織化学
    クインテッセンス 2002
  • Current Status of Endodontic Practice in Japan. (coauther)
    Asia-Pacific Endodontic Confederation, Program and Abstracts 2002
  • Defense Mechanisms of the Dental Pulp against Noxious Stimuli
    Asia-Pacific Endodontic Confederation, Program and Abstracts 2002
  • Dendritic Cells and Macrophages in the Pathologenesis of Periapical Lesions:A Phenotypic and Ultrastructural Analysis (coauther)
    Proceedings of the International Conference on Dentin/Pulp Complex 2001, Quintessence Publishing Co.,Ltd. 2002
ｍore...
Education (4)：
  • - 1991 Tokyo Medical and Dental University
  • - 1991 Tokyo Medical and Dental University Graduate School, Division of Dental Research
  • - 1986 Niigata University Faculty of Dentistry
  • - 1986 Niigata University Faculty of Dentistry
Professional career (1)：
  • PhD (Tokyo Medical and Dental University)
Work history (9)：
  • 2021 - 現在 東京医科歯科大学大学院医歯学総合研究科准教授
  • 2017 - 2021 東京医科歯科大学大学院医歯学総合研究科講師
  • 2008 - 2017 東京医科歯科大学大学院医歯学総合研究科助教
  • 2005 - 2008 東京医科歯科大学21世紀COE歯と骨の分子破壊と再構築のフロンティア 特任准教授
  • 2003 - 2005 東京医科歯科大学21世紀COE歯と骨の分子破壊と再構築のフロンティア 特任講師
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Association Membership(s) (10)：
日本NO学会 ,  日本歯内療法学会 ,  口腔病学会 ,  歯科基礎医学会 ,  日本歯科保存学会 ,  国際歯科研究会 (International Association for Dental Research) ,  Japanese Association for Endodontics ,  Japanese Association for Oral Biology ,  Japanese Association for Consevative Dentistry ,  International Association for Dental Research
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