Rchr
J-GLOBAL ID:200901003683508460
Update date: May. 09, 2024
Kawasaki Yoshihiro
カワサキ ヨシヒロ | Kawasaki Yoshihiro
Affiliation and department:
Research field (5):
Molecular biology
, Tumor biology
, Medical biochemistry
, Pathobiochemistry
, Cell biology
Research keywords (1):
腫瘍生物学
Research theme for competitive and other funds (13):
- 2021 - 2024 Analysis of a multifunctional Wnt/c-Myc target lncRNA in tumorigenesis
- 2020 - 2023 Development of cell function editing technology with fast 3D measurement and local-field light perturbation
- 2018 - 2023 高精度時空間計測による多元細胞情報統合
- 2017 - 2019 Search for novel Lgr5 ligands and receptor of Reg4
- 2016 - 2019 Elucidation of molecular mechanisms underlying colorectal tumorigenesis driven by Wnt/c-Myc signaling
- 2013 - 2016 Functional analysis of Lgr5 in colon and ovary cancer
- 2012 - 2014 癌抑制遺伝子産物APCが関わる上皮管腔形成機構とその破綻による癌発症機構の解明
- 2011 - 2012 Mechanisms of colon cancer stem cell self-renewal and pluripotency
- 2009 - 2010 The role of NMDA receptor/PSD-95/SPAL-1/Rap signaling in higher brain function
- 2005 - 2009 Molecular mechanism of tumor cell growth
- 2007 - 2008 Functional analysis of APC in neurite outgrowth
- 2005 - 2006 神経突起伸長におけるAPCの機能
- 2001 - 2003 癌抑制遺伝子APCの機能解析
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Papers (31):
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Yoshihiro Kawasaki, Tomoko Hamaji, Koji Owada, Akiko Hayashi, Yuping Wu, Taisaku Nogi, Miwa Okada, Shoko Sakai, Naoko Tokushige, Yuta Kouyama, et al. APC-mutant cells exploit compensatory chromosome alterations to restore tumour cell fitness. 2020
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Yoshihiro Kawasaki, Masaya Miyamoto, Takeaki Oda, Kosuke Matsumura, Lumi Negishi, Ryuichiro Nakato, Sakiko Suda, Naoko Yokota, Katsuhiko Shirahige, Tetsu Akiyama. The novel lnc RNA CALIC upregulates AXL to promote colon cancer metastasis. EMBO reports. 2019. 20. 8
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Masaya Miyamoto, Tomoatsu Hayashi, Yoshihiro Kawasaki, Tetsu Akiyama. Sp5 negatively regulates the proliferation of HCT116 cells by upregulating the transcription of p27. Oncology Letters. 2018
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Lesley S. Chaboub, Jeanne M. Manalo, Hyun Kyoung Lee, Stacey M. Glasgow, Fengju Chen, Yoshihiro Kawasaki, Tetsu Akiyama, Chay T. Kuo, Chad J. Creighton, Carrie A. Mohila, et al. Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles forAsefduring Development and after Injury. The Journal of Neuroscience. 2016. 36. 47. 11904-11917
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K Matsumura, Y Kawasaki, M Miyamoto, Y Kamoshida, J Nakamura, L Negishi, S Suda, T Akiyama. The novel G-quadruplex-containing long non-coding RNA GSEC antagonizes DHX36 and modulates colon cancer cell migration. Oncogene. 2016. 36. 9. 1191-1199
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MISC (4):
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川崎 善博, 宮本 昌弥, 松村 厚佑, 根岸 瑠美, 小田 健昭, 中戸 隆一郎, 須田 咲希子, 横田 直子, 白髭 克彦, 秋山 徹. 新規lncRNA CALICはAXLの発現を誘導して大腸がん細胞の転移を引き起こす(The novel lncRNA CALIC upregulates AXL to promote colon cancer metastasis). 日本癌学会総会記事. 2019. 78回. P-3255
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NEGISHI Lumi, TANIUE Kenzui, KAWASAKI Yoshihiro, MATSUMURA Kosuke, TAKAHASHI Akiko, AKIYAMA Tetsu. Proteomic analysis of the lncRNA-protein complexes in colon cancer cells. 生物物理(Web). 2017. 57. Supplement 1-2
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川崎善博, 小宮美文, 松村厚佑, 根岸瑠美, 須田咲希子, 奥野ます美, 横田直子, 長田知也, 長嶋剛史, 日吉雅也, et al. Wnt/c-Myc経路の新規標的lncRNA:MYUはCDK6の発現を誘導して細胞周期を進める. 日本分子生物学会年会プログラム・要旨集(Web). 2016. 39th
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T Akiyama, Y Kawasaki. Wnt signalling and the actin cytoskeleton. Oncogene. 2006. 25. 57. 7538-7544
Education (2):
- 2001 - 東京大学大学院 農学生命科学研究科
- 1996 - Osaka University School of Engineering
Work history (7):
Awards (2):
- 2011/10 - 日本癌学会 日本癌学会奨励賞
- 2004/02 - 井上科学振興財団 井上研究奨励賞
Association Membership(s) (4):
日本がん分子標的治療学会
, 日本細胞生物学会
, 日本分子生物学会
, 日本癌学会
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