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J-GLOBAL ID：200901003712760564 Update date: Oct. 16, 2024

Kambe Taiho

カンベタイホウ | Kambe Taiho

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://www.lif.kyoto-u.ac.jp/labs/seitaijoho/

Research field (1)： Applied biochemistry

Research keywords (8)：亜鉛 , 微量金属 , トランスポーター , copper , manganese , zinc , trace element , transporter

Research theme for competitive and other funds (19)：

2022 - 2025 Molecular mechanism and its physiological significance of metal coordination in Tyrosinase family proteins
2019 - 2024 Protein metalation that controls biometal dynamics in the cells
2019 - 2024 Integrated Biometal Science: Research to Explore Dynamics of Metals in Cellular System
2020 - 2023 Development of efficient purification methods and analyses of health-promoting functions for natural functional ingredients.
2019 - 2022 Clarification of the molecular mechanism how zinc deficiency is associated with IBD

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Papers (182)：

Hana Yuasa, Kiyoshi Miyazaki, Takamasa Kido, Katsutoshi Nishino, Miku Shiotsu, Tsutomu Fukuwatari, Machi Suka, Masaya Nagao, Taiho Kambe. Rate of hydrolysis of the phosphate esters of B vitamins is reduced by zinc deficiency: In vitro and in vivo. The FASEB Journal. 2024. 38. 18
Rong Cheng, Yuki Nishikawa, Takumi Wagatsuma, Taiho Kambe, Yu-Ki Tanaka, Yasumitsu Ogra, Tomonori Tamura, Itaru Hamachi. Protein-Labeling Reagents Selectively Activated by Copper(I). ACS chemical biology. 2024. 19. 6. 1222-1228
Hana Yuasa, Naho Morino, Takumi Wagatsuma, Masayuki Munekane, Sachiko Ueda, Mayu Matsunaga, Yasuo Uchida, Takane Katayama, Toshihiko Katoh, Taiho Kambe. ZNT5-6 and ZNT7 play an integral role in protein N-glycosylation by supplying Zn2+ to Golgi α-mannosidase II. Journal of Biological Chemistry. 2024. 300. 6. 107378-107378
Yukina Nishito, Hitomi Fujishiro, Shino Nagamatsu, Taiho Kambe. Reduced Mn uptake of pleiotropic ZIP8 SNP is caused by its loss of Mn-responsive accumulation on the cell-surface. Bioscience, biotechnology, and biochemistry. 2024
神戸大朋. 分泌経路における銅酵素と,亜鉛酵素の活性化機構. 生体の科学特集「生命現象を駆動する生体内金属動態の理解と展開」. 2024. 75. 2. 143-147

MISC (84)：

阪田雅実, 池田義人, 池田義人, 伊藤加奈子, 藤田菜々子, 山田泰之, 佐野紘平, 宗兼将之, 宗兼将之, 向高弘, et al. Screening of herbal medicines and examination of Pueraria root components that promote zinc uptake. 日本薬学会年会要旨集(Web). 2023. 143rd
池田義人, 川上瑞生, 山田泰之, 宗兼将之, 佐野紘平, 向高弘, 神戸大朋, 士反伸和. 生薬ニンジンによる亜鉛輸送体Zip4を介した亜鉛取り込みの促進. 日本生薬学会年会講演要旨集. 2023. 69th
藤代瞳, 田口央基, 神戸大朋, 姫野誠一郎, 姫野誠一郎, 角大悟. Investigation of the effect of metal binding motifs in the zinc transporter ZIP8 on Mn transport. Biomedical Research on Trace Elements (Web). 2021. 32. 2
藤代瞳, 神戸大朋. 亜鉛輸送体ZIP8の変異による全身性マンガン恒常性調節異常. 日本生化学会大会(Web). 2020. 93rd
藤代瞳, 宮本幸来, 神戸大朋, 姫野誠一郎, 姫野誠一郎. ヒトZIP8の多様なアミノ酸変異と金属結合モチーフがMn輸送に及ぼす影響の解析. Fundamental Toxicological Sciences (Web). 2020. 7. Supplement

Patents (2)：

Books (10)：

生命金属ダイナミクス;生体内における金属の挙動と制御
2021
亜鉛トランスポーターを介したエクト型亜鉛要求性酵素の活性
食品・バイオにおける最新の酵素応用, シーエムシー出版 2019
Biological functions of soyasaponins: The potential use to improve zinc nutrition
Elsevier 2018
Zinc transporters in health and disease
MOLECULAR NUTRITION OF MAJOR AND TRACE MINERALS 2015
“Introduction: “Zinc Signaling”-The Blossoming Field of Zinc Biology” Zinc Signals in Cellular Functions and Disorders, Fukada T, Kambe T (eds).
Tokyo: Springer, 1-5 2014

Lectures and oral presentations (101)：

Education (4)：

Professional career (1)：

Work history (5)：

Awards (12)：

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Association Membership(s) (10)：

International Society for Zinc Biology , アメリカ生化学・分子生物学会 , 日本農芸化学会 , 日本生化学会 , 日本分子生物学会 , 日本栄養・食糧学会 , 日本微量元素学会 , 日本亜鉛栄養治療研究会 , 日本微量栄養素学会 , 日本動物細胞工学会

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