Uchiyama Susumu

ウチヤマススム | Uchiyama Susumu

Affiliation and department：
Job title： Professor
Other affiliations (1)：

Homepage URL (1)： https://macromolecularbiotechnology.com

Research field (4)： Pharmaceuticals - analytical and physicochemistry , Biophysics , Structural biochemistry , Biochemistry

Research keywords (4)：遺伝子治療用ベクターの分析、品質管理、製剤 , バイオ医薬品の分析、品質管理と製剤 , 蛋白質溶液論 , Biophysical Chemistry of biological macromolecules

Research theme for competitive and other funds (20)：

2024 - 2027 Development of a Novel ALS Therapeutic Strategy Targeting Primary Sensory Neurons
2017 - 2022 次世代医薬品の効率的実用化推進のための品質評価技術基盤の開発
2018 - 2020 蛍光超遠心分析法による分子夾雑環境中での定量的相互作用解析
2017 - 2020 Physico-chemical and mathematical analyses of immune related signal induced by antibody aggregates
2016 - 2018 超分子質量分析による蛋白質複合体の離合集散過程の解明

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Papers (339)：

Rie Takino, Yuki Yamaguchi, Takahiro Maruno, Ekaputra Ramadhani, Misaki Furukawa, Tetsuo Torisu, Susumu Uchiyama. Physicochemical and biological impacts of light stress on adeno-associated virus serotype 6. Molecular Therapy - Methods & Clinical Development. 2024
Ryoji Nakatsuka, Yuki Yamaguchi, Kiichi Hirohata, Saki Shimojo, Makoto Murakami, Mark Allen Vergara Rocafort, Yasuo Tsunaka, Mitsuko Fukuhara, Tetsuo Torisu, Susumu Uchiyama. Multimass Analysis of Adeno-Associated Virus Vectors by Orbitrap-Based Charge Detection Mass Spectrometry. Analytical Chemistry. 2024
Sereirath Soth, Mikako Takakura, Masahiro Suekawa, Takayuki Onishi, Kiichi Hirohata, Tamami Hashimoto, Takahiro Maruno, Mitsuko Fukuhara, Yasuo Tsunaka, Tetsuo Torisu, et al. Quantification of full and empty particles of adeno-associated virus vectors via a novel dual fluorescence-linked immunosorbent assay. Molecular therapy. Methods & clinical development. 2024. 32. 3. 101291-101291
Kota Inoue, Yumiko Masuda, Tetsuo Torisu, Koichi Nonaka, Susumu Uchiyama. Prediction models for the flux decay profile and initial flux of microfiltration for therapeutic proteins. Biotechnology and Bioengineering. 2024. 121. 6. 1889-1901
Yuuki Koseki, Yuki Yamaguchi, Michihiko Aoyama, Minoru Tada, Akinobu Senoo, Akiko Ishii-Watabe, Takayuki Uchihashi, Susumu Uchiyama, Koichi Kato, Saeko Yanaka, et al. Key role of Pro230 in the hinge region on the IgG architecture and function. 2024

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MISC (239)：

Mizuguchi Junya, Torisu Tetsuo, Uchiyama Susumu. Quality and Physical Properties of Food Proteins. Foods & Food Ingredients Journal of Japan. 2023. 228. 2. 130-136
HARAZONO Akira, SHIBATA Hiroko, KIYOSHI Masato, TAKESHITA Rie, SHIMBO Kazutaka, MANNEN Teruhisa, TAKASUGI Tomohiro, HAYASHI Yu, AKIMARU Michiko, SAITO Shuntaro, et al. Interlaboratory Evaluation of the Analytical Performance of Size Exclusion Chromatography for Small Aggregates in Biopharmaceuticals and Considerations on Development of Analytical Procedures. Pharmaceutical and Medical Device Regulatory Science. 2022. 53. 6. 514-533
Yamaguchi Yuki, Uchiyama Susumu. Evaluation technique for the physical properties of antibody drugs. Drug Delivery System. 2021. 36. 5. 336-341
内山進, 馬場健史, 松田史生. 特集によせて. 生物工学会誌. 2021. 99. 6. 282-283
Maruno Takahiro, Uchiyama Susumu. Analyses of Isothermal Titration Calorimetry Data Using Program SEDPHAT. Netsu Sokutei. 2020. 47. 1. 14-18

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Patents (4)：

Books (7)：

バイオ医薬 : 基礎から開発まで
東京化学同人 2020 ISBN:9784807909810
ビジュアルバイオテクノロジー
化学同人 2017 ISBN:9784759819205
Analytical Ultracentrifugation, Instrumentation, Software, and Applications,
Springer 2016 ISBN:9784431559832
超遠心分析による蛋白質凝集体の評価
シーエムシー出版書籍 2015 ISBN:9784781310640
抗体の安定性の向上
シーエムシー出版 2012 ISBN:9784781306735

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Works (4)：

Education (3)：

Professional career (1)：

Work history (7)：

2018/04 - 現在 National Institutes of Natural Sciences ExCELLS
2017 - 現在 Osaka University
2020/04 - 2022/03 Kyoto University
2014/04 - 2018/03 National Institutes of Natural Sciences Okazaki Research Facilities Okazaki Institute for Integrative Bioscience
2012/02 - 2017/11 Osaka University Graduate School of Engineering

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Committee career (4)：

Awards (2)：

Association Membership(s) (8)：

日本抗体学会 , 日本遺伝子細胞治療学会 , American Society for Cell and Gene Therapy , 日本動物細胞工学会 , 分子生物学会 , 日本生物物理学会 , 日本蛋白質科学会 , 日本生物工学会

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